Prone positioning before extracorporeal membrane oxygenation for severe acute respiratory distress syndrome : A retrospective multicenter study
Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved..
OBJECTIVE: To evaluate the clinical outcomes of patients with severe acute respiratory distress syndrome (ARDS) subjected to prone positioning before extracorporeal membrane oxygenation (ECMO).
DESIGN: A retrospective analysis of a multicenter cohort was carried out.
SETTING: Patients admitted to the Intensive Care Units of 11 hospitals in Korea.
PATIENTS: Patients were divided into those who underwent prone positioning before ECMO (n=28) and those who did not (n=34).
INTERVENTIONS: None.
VARIABLES OF INTEREST: Thirty-day mortality, ECMO weaning failure rate, mechanical ventilation weaning success rate, mechanical ventilation-free days at day 60.
RESULTS: The prone group had lower median peak inspiratory pressure and lower median dynamic driving pressure before ECMO. Thirty-day mortality was 21% in the prone group and 41% in the non-prone group (p=0.098). The prone group also showed a lower ECMO weaning failure rate, and a higher mechanical ventilation weaning success rate and more mechanical ventilation-free days at day 60. In the non-prone group, median dynamic compliance marginally decreased shortly after ECMO, but no significant change was observed in the prone group.
CONCLUSIONS: Prone positioning before ECMO was not associated to increased mortality and tended to exert a protective effect.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
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| Enthalten in: |
Medicina intensiva - 43(2019), 7 vom: 30. Okt., Seite 402-409 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kim, W-Y [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 06.04.2020 Date Revised 26.03.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.medin.2018.04.013 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM286259222 |
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| 041 | |a eng | ||
| 100 | 1 | |a Kim, W-Y |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prone positioning before extracorporeal membrane oxygenation for severe acute respiratory distress syndrome |b A retrospective multicenter study |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 06.04.2020 | ||
| 500 | |a Date Revised 26.03.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved. | ||
| 520 | |a OBJECTIVE: To evaluate the clinical outcomes of patients with severe acute respiratory distress syndrome (ARDS) subjected to prone positioning before extracorporeal membrane oxygenation (ECMO) | ||
| 520 | |a DESIGN: A retrospective analysis of a multicenter cohort was carried out | ||
| 520 | |a SETTING: Patients admitted to the Intensive Care Units of 11 hospitals in Korea | ||
| 520 | |a PATIENTS: Patients were divided into those who underwent prone positioning before ECMO (n=28) and those who did not (n=34) | ||
| 520 | |a INTERVENTIONS: None | ||
| 520 | |a VARIABLES OF INTEREST: Thirty-day mortality, ECMO weaning failure rate, mechanical ventilation weaning success rate, mechanical ventilation-free days at day 60 | ||
| 520 | |a RESULTS: The prone group had lower median peak inspiratory pressure and lower median dynamic driving pressure before ECMO. Thirty-day mortality was 21% in the prone group and 41% in the non-prone group (p=0.098). The prone group also showed a lower ECMO weaning failure rate, and a higher mechanical ventilation weaning success rate and more mechanical ventilation-free days at day 60. In the non-prone group, median dynamic compliance marginally decreased shortly after ECMO, but no significant change was observed in the prone group | ||
| 520 | |a CONCLUSIONS: Prone positioning before ECMO was not associated to increased mortality and tended to exert a protective effect | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Decúbito prono | |
| 650 | 4 | |a Extracorporeal membrane oxygenation | |
| 650 | 4 | |a Oxigenación con membrana extracorpórea | |
| 650 | 4 | |a Prone position | |
| 650 | 4 | |a Respiración, artificial | |
| 650 | 4 | |a Respiration, artificial | |
| 650 | 4 | |a Respiratory distress syndrome, adult | |
| 650 | 4 | |a Síndrome de dificultad respiratoria, adulto | |
| 700 | 1 | |a Kang, B J |e verfasserin |4 aut | |
| 700 | 1 | |a Chung, C R |e verfasserin |4 aut | |
| 700 | 1 | |a Park, S H |e verfasserin |4 aut | |
| 700 | 1 | |a Oh, J Y |e verfasserin |4 aut | |
| 700 | 1 | |a Park, S Y |e verfasserin |4 aut | |
| 700 | 1 | |a Cho, W H |e verfasserin |4 aut | |
| 700 | 1 | |a Sim, Y S |e verfasserin |4 aut | |
| 700 | 1 | |a Cho, Y-J |e verfasserin |4 aut | |
| 700 | 1 | |a Park, S |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, J-H |e verfasserin |4 aut | |
| 700 | 1 | |a Hong, S-B |e verfasserin |4 aut | |
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