Effects of Restraint Manipulation on Learning-memory Ability, Visional Acuity and Body Mass of Rats

OBJECTIVE: Restraint manipulation is necessary for observing the effect of acupuncture or moxibustion stimulation on various variables in the experimental study. Thus, the present study was designed to examine the impact of restraint manipulation on rats' learning-memory ability, visional acuity, and body mass, so as to have a reasonable assessment on the influence of restraint stress.

METHODS: Normal Sprague Dawley rats were randomly assigned to a restraint group (n=15) and a control group (n=15). In the restraint group, self-made restraint devices were used to bind the rats for 30 min daily for 30 consecutive days. The body mass of the rats was monitored daily; and the learningmemory ability and the visional acuity assessed using visual water task.

RESULTS: After 30 days' restraint, no significant differences were found between the two groups in the training times for acquiring a correct rate of 80% in the learning-memory tests, and visional acuity and body mass (P ﹥0.05).

CONCLUSION: Thirty days' restraint has no obvious impact on the increase of body weight, learning-memory and visional acuity in normal rats, suggesting an applicable of restraint device in acupuncture study.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:43

Enthalten in:

Zhen ci yan jiu = Acupuncture research - 43(2018), 4 vom: 25. Apr., Seite 247-50

Sprache:

Chinesisch

Beteiligte Personen:

Chen, Mei-Qing [VerfasserIn]
Ma, Xian-Zhen [VerfasserIn]
Bi, Ai-Ling [VerfasserIn]
Sun, Yuan-Yuan [VerfasserIn]
Zhang, Xiu-Yan [VerfasserIn]
Chen, Rong [VerfasserIn]
Bi, Hong-Sheng [VerfasserIn]

Links:

Volltext

Themen:

Body mass
Journal Article
Learning-memory ability
Restraint manipulation
Stress
Visional acuity

Anmerkungen:

Date Completed 03.04.2019

Date Revised 03.04.2019

published: Print

Citation Status MEDLINE

doi:

10.13702/j.1000-0607.170551

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM285330918