Plasma prolidase levels as a biomarker for polycystic ovary syndrome
AIM: Assessment of plasma prolidase levels in polycystic ovary syndrome (PCOS).
PATIENTS & METHODS: PCOS patients were screened according to Rotterdam Criterion and prolidase levels were measured.
RESULTS: A total of 170 patients and 160 controls were recruited for the study and it was found that prolidase levels were significantly higher in PCOS group (991.10 ± 39.52) than control (621.89 ± 23.94). Furthermore it has been found that prolidase levels increase with the number of cysts in ovaries.
CONCLUSION: Significant difference between prolidase levels in PCOS and control shows that it may be used as a diagnostic marker for disease. In addition to this, there is a positive correlation found between prolidase levels and number of cysts, hence may be used as a prognostic marker to monitor disease status.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Biomarkers in medicine - 12(2018), 6 vom: 15. Juni, Seite 597-606 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bhatnager, Richa [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 22.07.2019 Date Revised 22.07.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2217/bmm-2017-0306 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM285183974 |
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| 245 | 1 | 0 | |a Plasma prolidase levels as a biomarker for polycystic ovary syndrome |
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| 500 | |a Date Completed 22.07.2019 | ||
| 500 | |a Date Revised 22.07.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a AIM: Assessment of plasma prolidase levels in polycystic ovary syndrome (PCOS) | ||
| 520 | |a PATIENTS & METHODS: PCOS patients were screened according to Rotterdam Criterion and prolidase levels were measured | ||
| 520 | |a RESULTS: A total of 170 patients and 160 controls were recruited for the study and it was found that prolidase levels were significantly higher in PCOS group (991.10 ± 39.52) than control (621.89 ± 23.94). Furthermore it has been found that prolidase levels increase with the number of cysts in ovaries | ||
| 520 | |a CONCLUSION: Significant difference between prolidase levels in PCOS and control shows that it may be used as a diagnostic marker for disease. In addition to this, there is a positive correlation found between prolidase levels and number of cysts, hence may be used as a prognostic marker to monitor disease status | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a PCOS | |
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| 650 | 4 | |a collagen | |
| 650 | 4 | |a diagnostic marker | |
| 650 | 4 | |a extracellular matrix | |
| 650 | 4 | |a polycystic ovaries | |
| 650 | 4 | |a prognostic marker | |
| 650 | 4 | |a prolidase | |
| 650 | 4 | |a transvaginal ultrasonography | |
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