Systemic thrombolysis after the administration of idarucizumab in acute ischemic stroke
Introduction - Expanding indications have resulted in an increasing number of patients taking novel oral anticoagulants, posing a major treatment dilemma in acute ischemic stroke. Case presentation - We present a successful intravenous thrombolysis in a dabigatran-treated patient with acute ischemic stroke after the administration of idarucizumab. Discussion - According to current guidelines, systemic thrombolysis is contraindicated under treatment with novel oral anticoagulants (taken within 48 hours). In this scenario, idarucizumab offers a solution by reversing the anticoagulant effect of dabigatran. Conclusion - Although there have only been case reports published so far, the dabigatran-antidote idarucizumab seems to give new therapeutic opportunities in the treatment of acute ischemic stroke.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:70 |
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| Enthalten in: |
Ideggyogyaszati szemle - 70(2017), 7-8 vom: 30. Juli, Seite 284-288 |
| Sprache: |
Ungarisch |
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| Weiterer Titel: |
Idarucizumab adását követően elvégzett szisztémás thrombolysis akut ischaemiás stroke-ban |
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| Beteiligte Personen: |
Pásztor, Máté [VerfasserIn] |
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| Links: |
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| Themen: |
97RWB5S1U6 |
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| Anmerkungen: |
Date Completed 24.01.2019 Date Revised 24.01.2019 published: Print Citation Status MEDLINE |
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| doi: |
10.18071/isz.70.0284 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM285155911 |
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| 245 | 1 | 0 | |a Systemic thrombolysis after the administration of idarucizumab in acute ischemic stroke |
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| 500 | |a published: Print | ||
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| 520 | |a Introduction - Expanding indications have resulted in an increasing number of patients taking novel oral anticoagulants, posing a major treatment dilemma in acute ischemic stroke. Case presentation - We present a successful intravenous thrombolysis in a dabigatran-treated patient with acute ischemic stroke after the administration of idarucizumab. Discussion - According to current guidelines, systemic thrombolysis is contraindicated under treatment with novel oral anticoagulants (taken within 48 hours). In this scenario, idarucizumab offers a solution by reversing the anticoagulant effect of dabigatran. Conclusion - Although there have only been case reports published so far, the dabigatran-antidote idarucizumab seems to give new therapeutic opportunities in the treatment of acute ischemic stroke | ||
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