Steroid-resistant focal segmental glomerulosclerosis treated with cascade plasmafiltration and rituximab
Copyright by Società Italiana di Nefrologia SIN, Rome, Italy..
A 39-year man with primary steroid resistant focal segmental glomerulosclerosis (FSGS) was treated with mycophenolate mofetil and ACE-inhibitors. After six months a different therapeutics approach was mandatory due to the worsening of renal function and the relapse of proteinuria at the nephrotic range. The combination of cascade plasmafiltration and single dose of rituximab (375 mg/m²) achieved clinical remission and improved renal function in six months follow up. Cascade plasmafiltration in association with rituximab can be considered as a salvage method for primary steroid-resistant FSGS. Clinical trials should be carried out for protocol approval.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2018 |
|---|---|
| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
|---|---|
| Enthalten in: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia - 35(2018), 3 vom: 22. Mai |
| Sprache: |
Italienisch |
|---|
| Beteiligte Personen: |
Tatangelo, Paola [VerfasserIn] |
|---|
| Anmerkungen: |
Date Completed 21.06.2019 Date Revised 21.06.2019 published: Print Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM284322407 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM284322407 | ||
| 003 | DE-627 | ||
| 005 | 20231225042938.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2018 xx |||||o 00| ||ita c | ||
| 028 | 5 | 2 | |a pubmed24n0947.xml |
| 035 | |a (DE-627)NLM284322407 | ||
| 035 | |a (NLM)29786187 | ||
| 035 | |a (PII)2018-vol3 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a ita | ||
| 100 | 1 | |a Tatangelo, Paola |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Steroid-resistant focal segmental glomerulosclerosis treated with cascade plasmafiltration and rituximab |
| 264 | 1 | |c 2018 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 21.06.2019 | ||
| 500 | |a Date Revised 21.06.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright by Società Italiana di Nefrologia SIN, Rome, Italy. | ||
| 520 | |a A 39-year man with primary steroid resistant focal segmental glomerulosclerosis (FSGS) was treated with mycophenolate mofetil and ACE-inhibitors. After six months a different therapeutics approach was mandatory due to the worsening of renal function and the relapse of proteinuria at the nephrotic range. The combination of cascade plasmafiltration and single dose of rituximab (375 mg/m²) achieved clinical remission and improved renal function in six months follow up. Cascade plasmafiltration in association with rituximab can be considered as a salvage method for primary steroid-resistant FSGS. Clinical trials should be carried out for protocol approval | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a cascade plasmafiltration | |
| 650 | 4 | |a focal segmental glomerular sclerosis | |
| 650 | 4 | |a rituximab | |
| 650 | 4 | |a steroid-resistant focal segmental glomerular sclerosis | |
| 650 | 7 | |a Adrenal Cortex Hormones |2 NLM | |
| 650 | 7 | |a Angiotensin-Converting Enzyme Inhibitors |2 NLM | |
| 650 | 7 | |a Diuretics |2 NLM | |
| 650 | 7 | |a Immunosuppressive Agents |2 NLM | |
| 650 | 7 | |a Platelet Aggregation Inhibitors |2 NLM | |
| 650 | 7 | |a Rituximab |2 NLM | |
| 650 | 7 | |a 4F4X42SYQ6 |2 NLM | |
| 650 | 7 | |a Atorvastatin |2 NLM | |
| 650 | 7 | |a A0JWA85V8F |2 NLM | |
| 650 | 7 | |a Mycophenolic Acid |2 NLM | |
| 650 | 7 | |a HU9DX48N0T |2 NLM | |
| 700 | 1 | |a Londrino, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Di Vasta, Giorgio |e verfasserin |4 aut | |
| 700 | 1 | |a Guido, Giuliana |e verfasserin |4 aut | |
| 700 | 1 | |a Centi, Alessia |e verfasserin |4 aut | |
| 700 | 1 | |a Dominijanni, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Bernabei, Eleonora |e verfasserin |4 aut | |
| 700 | 1 | |a Caramiello, Maria Stella |e verfasserin |4 aut | |
| 700 | 1 | |a Di Franco, Damiano |e verfasserin |4 aut | |
| 700 | 1 | |a Palumbo, Roberto |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia |d 1997 |g 35(2018), 3 vom: 22. Mai |w (DE-627)NLM093699778 |x 1724-5990 |7 nnns |
| 773 | 1 | 8 | |g volume:35 |g year:2018 |g number:3 |g day:22 |g month:05 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 35 |j 2018 |e 3 |b 22 |c 05 | ||