Pharmacology behind Common Drug Nephrotoxicities
Copyright © 2018 by the American Society of Nephrology..
Patients are exposed to numerous prescribed and over-the-counter medications. Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A combination of factors including the innate nephrotoxicity of drugs, underlying patient characteristics that increase their risk for kidney injury, and the metabolism and pathway of excretion by the kidneys of the various agents administered enhance risk for drug-induced nephrotoxicity. This paper will review these clinically relevant aspects of drug-induced nephrotoxicity for the clinical nephrologist.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Clinical journal of the American Society of Nephrology : CJASN - 13(2018), 12 vom: 07. Dez., Seite 1897-1908 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Perazella, Mark A [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 11.12.2019 Date Revised 13.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2215/CJN.00150118 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM282717773 |
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| 520 | |a Copyright © 2018 by the American Society of Nephrology. | ||
| 520 | |a Patients are exposed to numerous prescribed and over-the-counter medications. Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A combination of factors including the innate nephrotoxicity of drugs, underlying patient characteristics that increase their risk for kidney injury, and the metabolism and pathway of excretion by the kidneys of the various agents administered enhance risk for drug-induced nephrotoxicity. This paper will review these clinically relevant aspects of drug-induced nephrotoxicity for the clinical nephrologist | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Acute Kidney Injury | |
| 650 | 4 | |a Drug Transporters | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Nephrologists | |
| 650 | 4 | |a Nonprescription Drugs | |
| 650 | 4 | |a Pharmacology | |
| 650 | 4 | |a Proximal Tubulopathy | |
| 650 | 4 | |a Renal Elimination | |
| 650 | 4 | |a Risk | |
| 650 | 4 | |a acute renal failure | |
| 650 | 4 | |a drug nephrotoxicity | |
| 650 | 4 | |a kidney | |
| 650 | 4 | |a metabolism | |
| 650 | 7 | |a Prescription Drugs |2 NLM | |
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