In vitro combination of voriconazole with micafungin against azole-resistant clinical isolates of Aspergillus fumigatus from different geographical regions
Copyright © 2018 Elsevier Inc. All rights reserved..
In vitro interaction of voriconazole with micafungin was evaluated against 33 clinical Aspergillus fumigatus isolates, including azole-resistant (n=31) and -susceptible (n=2) isolates. Interaction was synergistic for only 1 resistant isolate carrying the TR34/L98H mutation. No antagonistic effects were observed for 96.8% of azole-resistant isolates.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:91 |
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| Enthalten in: |
Diagnostic microbiology and infectious disease - 91(2018), 3 vom: 01. Juli, Seite 266-268 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Fakhim, Hamed [VerfasserIn] |
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| Links: |
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| Themen: |
Antifungal Agents |
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| Anmerkungen: |
Date Completed 28.09.2018 Date Revised 02.12.2018 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.diagmicrobio.2018.03.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM282713956 |
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| 520 | |a In vitro interaction of voriconazole with micafungin was evaluated against 33 clinical Aspergillus fumigatus isolates, including azole-resistant (n=31) and -susceptible (n=2) isolates. Interaction was synergistic for only 1 resistant isolate carrying the TR34/L98H mutation. No antagonistic effects were observed for 96.8% of azole-resistant isolates | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Dannaoui, Eric |e verfasserin |4 aut | |
| 700 | 1 | |a Sharma, Cheshta |e verfasserin |4 aut | |
| 700 | 1 | |a Mousavi, Bita |e verfasserin |4 aut | |
| 700 | 1 | |a Chowdhary, Anuradha |e verfasserin |4 aut | |
| 700 | 1 | |a Meis, Jacques F |e verfasserin |4 aut | |
| 700 | 1 | |a Badali, Hamid |e verfasserin |4 aut | |
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