Relevance of 25 (OH) Vitamin D deficiency on Hashimoto's Thyroiditis
Copyright© by the Egyptian Association of Immunologists..
An association between low levels of vitamin D and Hashimoto's thyroiditis was suggested. This study aimed to determine the status of 25 (OH) vitamin D in Hashimoto's thyroiditis. A case-control study was designed, a Hashimoto's thyroiditis patient group (n=30) and two control groups including Graves' disease (30) and a healthy control group (20). TSH, Free T3, Free T4, antithyroid antibodies (antithyroglobulin and antithyroid peroxidase), calcium and serum 25 (OH) vitamin D were assessed. Vitamin D and calcium levels were significantly lower in Hashimoto thyroiditis and Graves' disease versus healthy controls. Vitamin D was deficient in 76.7% of Hashimoto thyroiditis and 70% of Graves' disease compared to 20.0% of healthy control, and negatively correlated with antithyroglobulin and antithyroid peroxidase in Hashimoto's thyroiditis group. Vitamin D is recommended for patients with vitamin D deficiency. Further investigations are needed to evaluate the preventive and therapeutic effects of vitamin D in autoimmune thyroid disease.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
The Egyptian journal of immunology - 24(2017), 2 vom: 18. Juni, Seite 53-62 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bakr, Hoda G [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 26.04.2019 Date Revised 26.04.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM281850607 |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright© by the Egyptian Association of Immunologists. | ||
| 520 | |a An association between low levels of vitamin D and Hashimoto's thyroiditis was suggested. This study aimed to determine the status of 25 (OH) vitamin D in Hashimoto's thyroiditis. A case-control study was designed, a Hashimoto's thyroiditis patient group (n=30) and two control groups including Graves' disease (30) and a healthy control group (20). TSH, Free T3, Free T4, antithyroid antibodies (antithyroglobulin and antithyroid peroxidase), calcium and serum 25 (OH) vitamin D were assessed. Vitamin D and calcium levels were significantly lower in Hashimoto thyroiditis and Graves' disease versus healthy controls. Vitamin D was deficient in 76.7% of Hashimoto thyroiditis and 70% of Graves' disease compared to 20.0% of healthy control, and negatively correlated with antithyroglobulin and antithyroid peroxidase in Hashimoto's thyroiditis group. Vitamin D is recommended for patients with vitamin D deficiency. Further investigations are needed to evaluate the preventive and therapeutic effects of vitamin D in autoimmune thyroid disease | ||
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