Diagnosis and treatment of primary antibody deficiency syndromes

Primary antibody deficiencies (PAD) make up more than half of primary immunodeficiencies. PAD is characterized by low levels of one or more immunoglobulin (Ig) classes or impaired vaccine response. Recurrent infections are the predominant presenting symptoms, but autoimmune disorders are also frequent. Onset of symptoms is often after the age of six. Screening for PAD with measurement of the levels of serum IgG, IgM, and IgA is simple and can be done in general practice. Replacement therapy with Ig is the cornerstone in treatment of PAD and reduces the frequency of infections and mortality.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:180

Enthalten in:

Ugeskrift for laeger - 180(2018), 9 vom: 26. Feb.

Sprache:

Dänisch

Beteiligte Personen:

Larsen, Carsten Schade [VerfasserIn]
Katzenstein, Terese L [VerfasserIn]

Themen:

Immunoglobulins
Journal Article
Review

Anmerkungen:

Date Completed 15.03.2019

Date Revised 15.03.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM281636788