Formulation possibilities of self-emulsifying drug deliv- ery systems, microemulsions and nanoemulsions.
Objective The aim of this review is to introduce the self-emulsifying drug delivery systems which can be used to improved the bioavailability of poorly water soluble drug substances. Methods The review summarizes the most prominent results of the lipid based medicinal preparations, such as microemulsions and nanoemulsions developed in the last two decades. Results The analysis of the references details the lipid based formulation classification systems, the most common excipients, the quality attributes depending on the ingredients, as well as the differences in the characteristics of micro- and nanoemulsions. Conclusions The summary demonstrates the formulation possibilities of self-emulsifying drug delivery systems, which may increase the applicability and are promising to improve the therapeutic effectiveness.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2017 |
|---|---|
| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
|---|---|
| Enthalten in: |
Acta pharmaceutica Hungarica - 87(2017), 1 vom: 22., Seite 27-34 |
| Sprache: |
Ungarisch |
|---|
| Weiterer Titel: |
Not available |
|---|
| Beteiligte Personen: |
Jakab, G [VerfasserIn] |
|---|
| Themen: |
Drug Carriers |
|---|
| Anmerkungen: |
Date Completed 03.04.2018 Date Revised 03.04.2018 published: Print Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM281469458 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM281469458 | ||
| 003 | DE-627 | ||
| 005 | 20231225031717.0 | ||
| 007 | tu | ||
| 008 | 231225s2017 xx ||||| 00| ||hun c | ||
| 028 | 5 | 2 | |a pubmed24n0938.xml |
| 035 | |a (DE-627)NLM281469458 | ||
| 035 | |a (NLM)29489095 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a hun | ||
| 100 | 1 | |a Jakab, G |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Formulation possibilities of self-emulsifying drug deliv- ery systems, microemulsions and nanoemulsions. |
| 246 | 3 | 3 | |a Not available |
| 264 | 1 | |c 2017 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 03.04.2018 | ||
| 500 | |a Date Revised 03.04.2018 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Objective The aim of this review is to introduce the self-emulsifying drug delivery systems which can be used to improved the bioavailability of poorly water soluble drug substances. Methods The review summarizes the most prominent results of the lipid based medicinal preparations, such as microemulsions and nanoemulsions developed in the last two decades. Results The analysis of the references details the lipid based formulation classification systems, the most common excipients, the quality attributes depending on the ingredients, as well as the differences in the characteristics of micro- and nanoemulsions. Conclusions The summary demonstrates the formulation possibilities of self-emulsifying drug delivery systems, which may increase the applicability and are promising to improve the therapeutic effectiveness | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Drug Carriers |2 NLM | |
| 650 | 7 | |a Emulsifying Agents |2 NLM | |
| 650 | 7 | |a Emulsions |2 NLM | |
| 650 | 7 | |a Lipids |2 NLM | |
| 700 | 1 | |a Fülöp, V |e verfasserin |4 aut | |
| 700 | 1 | |a Santha, K |e verfasserin |4 aut | |
| 700 | 1 | |a Szeröczei, D |e verfasserin |4 aut | |
| 700 | 1 | |a Balogh, E |e verfasserin |4 aut | |
| 700 | 1 | |a Antal, L |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta pharmaceutica Hungarica |d 1965 |g 87(2017), 1 vom: 22., Seite 27-34 |w (DE-627)NLM000024872 |x 0001-6659 |7 nnns |
| 773 | 1 | 8 | |g volume:87 |g year:2017 |g number:1 |g day:22 |g pages:27-34 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 87 |j 2017 |e 1 |b 22 |h 27-34 | ||