Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides
Copyright © 2018 Elsevier Ltd. All rights reserved..
The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
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| Enthalten in: |
Current opinion in cell biology - 50(2018) vom: 02. Feb., Seite 72-78 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Phua, Siew Cheng [VerfasserIn] |
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| Links: |
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| Themen: |
Actins |
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| Anmerkungen: |
Date Completed 14.01.2019 Date Revised 22.02.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ceb.2018.01.008 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia | ||
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