Electrophysiological characteristics and catheter ablation of symptomatic focal premature atrial contractions originating from pulmonary veins and non-pulmonary veins
© 2018 Wiley Periodicals, Inc..
BACKGROUND: We aimed to explore electrophysiological characteristics of premature atrial contractions (PACs) originating from pulmonary veins (PVs) and non-PVs and to evaluate the effectiveness and safety of catheter ablation for PACs.
HYPOTHESIS: Symptomatic PACs originated from different positions and whether could be ablated.
METHODS: Symptomatic, frequent, and drug-refractory PAC patients were enrolled in this study. All patients underwent electrophysiological study and catheter ablation.
RESULTS: A total of 81 patients were enrolled: 45 patients with PACs originating from PVs (group A), 24 patients with PACs originating from non-PVs (group B), and 12 patients with PACs arising from both PVs and non-PVs (group C). Twenty (44.4%) patients in group A, 6 (50.0%) patients in group C, and 3 (12.5%) patients in group B presented paroxysmal atrial fibrillation (P < 0.05). PV isolation was performed in groups A and C. Focal ablation or superior vena cava isolation was performed in groups B and C, depending on patient condition. PACs were abolished in all patients except one patient in group B. During a median follow-up period of 21.3 ± 14.3 months, 40 (88.9%) patients in group A, 10 (83.3%) patients in group C, and 21 (87.5%) patients in group B were free of recurrence after initial ablation.
CONCLUSIONS: Frequent PACs originating from PVs were associated with increased incidence of atrial fibrillation compared with PACs originating from non-PVs. Catheter ablation yields a satisfactory success rate and could be a good choice for eliminating symptomatic, frequent, and drug-refractory PACs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:41 |
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| Enthalten in: |
Clinical cardiology - 41(2018), 1 vom: 01. Jan., Seite 74-80 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Huang, Xingfu [VerfasserIn] |
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| Links: |
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| Themen: |
Atrial Fibrillation |
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| Anmerkungen: |
Date Completed 22.08.2018 Date Revised 09.01.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/clc.22853 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM280298684 |
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| 245 | 1 | 0 | |a Electrophysiological characteristics and catheter ablation of symptomatic focal premature atrial contractions originating from pulmonary veins and non-pulmonary veins |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2018 Wiley Periodicals, Inc. | ||
| 520 | |a BACKGROUND: We aimed to explore electrophysiological characteristics of premature atrial contractions (PACs) originating from pulmonary veins (PVs) and non-PVs and to evaluate the effectiveness and safety of catheter ablation for PACs | ||
| 520 | |a HYPOTHESIS: Symptomatic PACs originated from different positions and whether could be ablated | ||
| 520 | |a METHODS: Symptomatic, frequent, and drug-refractory PAC patients were enrolled in this study. All patients underwent electrophysiological study and catheter ablation | ||
| 520 | |a RESULTS: A total of 81 patients were enrolled: 45 patients with PACs originating from PVs (group A), 24 patients with PACs originating from non-PVs (group B), and 12 patients with PACs arising from both PVs and non-PVs (group C). Twenty (44.4%) patients in group A, 6 (50.0%) patients in group C, and 3 (12.5%) patients in group B presented paroxysmal atrial fibrillation (P < 0.05). PV isolation was performed in groups A and C. Focal ablation or superior vena cava isolation was performed in groups B and C, depending on patient condition. PACs were abolished in all patients except one patient in group B. During a median follow-up period of 21.3 ± 14.3 months, 40 (88.9%) patients in group A, 10 (83.3%) patients in group C, and 21 (87.5%) patients in group B were free of recurrence after initial ablation | ||
| 520 | |a CONCLUSIONS: Frequent PACs originating from PVs were associated with increased incidence of atrial fibrillation compared with PACs originating from non-PVs. Catheter ablation yields a satisfactory success rate and could be a good choice for eliminating symptomatic, frequent, and drug-refractory PACs | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Atrial Fibrillation | |
| 650 | 4 | |a Catheter Ablation | |
| 650 | 4 | |a Electrophysiological Techniques | |
| 650 | 4 | |a Premature Atrial Contractions | |
| 650 | 4 | |a Pulmonary Vein Isolation | |
| 700 | 1 | |a Chen, Yanjia |e verfasserin |4 aut | |
| 700 | 1 | |a Xiao, Junhui |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Hongxin |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Yizhen |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Shenrong |e verfasserin |4 aut | |
| 700 | 1 | |a He, Liwei |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Zheng |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Haobin |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Dingli |e verfasserin |4 aut | |
| 700 | 1 | |a Peng, Jian |e verfasserin |4 aut | |
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