Construction of tunable peptide nucleic acid junctions
We report here the construction of 3-way and 4-way peptide nucleic acid (PNA) junctions as basic structural units for PNA nanostructuring. The incorporation of amino acid residues into PNA chains makes PNA nanostructures with more structural complexity and architectural flexibility possible, as exemplified by building 3-way PNA junctions with tunable nanopores. Given that PNA nanostructures have good thermal and enzymatic stabilities, they are expected to have broad potential applications in biosensing, drug delivery and bioengineering.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:54 |
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| Enthalten in: |
Chemical communications (Cambridge, England) - 54(2018), 23 vom: 15. März, Seite 2846-2849 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Duan, Tanghui [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 06.04.2018 Date Revised 06.04.2018 published: Print Citation Status MEDLINE |
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| doi: |
10.1039/c8cc00108a |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a We report here the construction of 3-way and 4-way peptide nucleic acid (PNA) junctions as basic structural units for PNA nanostructuring. The incorporation of amino acid residues into PNA chains makes PNA nanostructures with more structural complexity and architectural flexibility possible, as exemplified by building 3-way PNA junctions with tunable nanopores. Given that PNA nanostructures have good thermal and enzymatic stabilities, they are expected to have broad potential applications in biosensing, drug delivery and bioengineering | ||
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| 700 | 1 | |a He, Liu |e verfasserin |4 aut | |
| 700 | 1 | |a Tokura, Yu |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Xin |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Yuzhou |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Zhengshuang |e verfasserin |4 aut | |
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