Effect of Daily Exposure to an Isolated Soy Protein Supplement on Body Composition, Energy and Macronutrient Intake, Bone Formation Markers, and Lipid Profile in Children in Colombia
A soy protein-based supplement may optimize bone health, support physical growth, and stimulate bone formation. This study aimed to assess the effect of a daily soy protein supplement (SPS) on nutritional status, bone formation markers, lipid profile, and daily energy and macronutrient intake in children. One hundred seven participants (62 girls), ages 2 to 9, started the study and were randomly assigned to lunch fruit juice with (n = 57, intervention group) or without (n = 50, control group) addition of 45 g (230 Kcal) of a commercial SPS during 12 months; 84 children (51 girls, 33 boys) completed the study (45 and 39 intervention and control, respectively). Nutritional assessment included anthropometry and nutrient intakes; initial and final blood samples were taken; insulin-like growth factor-I (IGF-I), osteocalcin, bone specific alkaline phosphatase (BAP), insulin-like growth factor binding protein-3 (IGFBP-3), cholesterol, triglycerides, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were analyzed. Statistically significant changes (p < .05) in body mass index and weight for age Z scores were observed between groups while changes in body composition were not. Changes in energy, total protein, and carbohydrate intakes were significantly higher in the intervention group (p < .01). Calorie intake changes were statistically significant between groups (p < .001), and BAP decreased in both groups, with values within normal ranges. Osteocalcin, IGFBP-3, and lipid profile were not different between groups. IGF-I levels and IGF/IGFBP-3 ratio increased significantly in both groups. In conclusion, changes in macronutrient and energy intake and nutritional status in the intervention group compared to control group may ensure harmonious and adequate bone health and development.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2019 |
---|---|
Erschienen: |
2019 |
Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
---|---|
Enthalten in: |
Journal of dietary supplements - 16(2019), 1 vom: 02., Seite 1-13 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Mejía, Wilson [VerfasserIn] |
---|
Links: |
---|
Anmerkungen: |
Date Completed 17.05.2019 Date Revised 10.12.2019 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1080/19390211.2017.1409851 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM279989156 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM279989156 | ||
003 | DE-627 | ||
005 | 20231225024317.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2019 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1080/19390211.2017.1409851 |2 doi | |
028 | 5 | 2 | |a pubmed24n0933.xml |
035 | |a (DE-627)NLM279989156 | ||
035 | |a (NLM)29336700 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Mejía, Wilson |e verfasserin |4 aut | |
245 | 1 | 0 | |a Effect of Daily Exposure to an Isolated Soy Protein Supplement on Body Composition, Energy and Macronutrient Intake, Bone Formation Markers, and Lipid Profile in Children in Colombia |
264 | 1 | |c 2019 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 17.05.2019 | ||
500 | |a Date Revised 10.12.2019 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a A soy protein-based supplement may optimize bone health, support physical growth, and stimulate bone formation. This study aimed to assess the effect of a daily soy protein supplement (SPS) on nutritional status, bone formation markers, lipid profile, and daily energy and macronutrient intake in children. One hundred seven participants (62 girls), ages 2 to 9, started the study and were randomly assigned to lunch fruit juice with (n = 57, intervention group) or without (n = 50, control group) addition of 45 g (230 Kcal) of a commercial SPS during 12 months; 84 children (51 girls, 33 boys) completed the study (45 and 39 intervention and control, respectively). Nutritional assessment included anthropometry and nutrient intakes; initial and final blood samples were taken; insulin-like growth factor-I (IGF-I), osteocalcin, bone specific alkaline phosphatase (BAP), insulin-like growth factor binding protein-3 (IGFBP-3), cholesterol, triglycerides, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were analyzed. Statistically significant changes (p < .05) in body mass index and weight for age Z scores were observed between groups while changes in body composition were not. Changes in energy, total protein, and carbohydrate intakes were significantly higher in the intervention group (p < .01). Calorie intake changes were statistically significant between groups (p < .001), and BAP decreased in both groups, with values within normal ranges. Osteocalcin, IGFBP-3, and lipid profile were not different between groups. IGF-I levels and IGF/IGFBP-3 ratio increased significantly in both groups. In conclusion, changes in macronutrient and energy intake and nutritional status in the intervention group compared to control group may ensure harmonious and adequate bone health and development | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Randomized Controlled Trial | |
650 | 4 | |a Colombia | |
650 | 4 | |a child | |
650 | 4 | |a dietary supplements | |
650 | 4 | |a nutritional status | |
650 | 4 | |a soybean proteins | |
650 | 7 | |a Biomarkers |2 NLM | |
650 | 7 | |a IGF1 protein, human |2 NLM | |
650 | 7 | |a IGFBP3 protein, human |2 NLM | |
650 | 7 | |a Insulin-Like Growth Factor Binding Protein 3 |2 NLM | |
650 | 7 | |a Lipids |2 NLM | |
650 | 7 | |a Soybean Proteins |2 NLM | |
650 | 7 | |a Insulin-Like Growth Factor I |2 NLM | |
650 | 7 | |a 67763-96-6 |2 NLM | |
650 | 7 | |a Alkaline Phosphatase |2 NLM | |
650 | 7 | |a EC 3.1.3.1 |2 NLM | |
700 | 1 | |a Córdoba, Diana |e verfasserin |4 aut | |
700 | 1 | |a Durán, Paola |e verfasserin |4 aut | |
700 | 1 | |a Chacón, Yersson |e verfasserin |4 aut | |
700 | 1 | |a Rosselli, Diego |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of dietary supplements |d 2008 |g 16(2019), 1 vom: 02., Seite 1-13 |w (DE-627)NLM192571656 |x 1939-022X |7 nnns |
773 | 1 | 8 | |g volume:16 |g year:2019 |g number:1 |g day:02 |g pages:1-13 |
856 | 4 | 0 | |u http://dx.doi.org/10.1080/19390211.2017.1409851 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 16 |j 2019 |e 1 |b 02 |h 1-13 |