Frailty Testing Pilot Study : Pros and Pitfalls
BACKGROUND: Frailty can be defined as an inflammatory state with a loss of physiologic reserve in multiple systems that manifests as a decreased ability to respond to stressors that ultimately leads to an increased risk of adverse outcomes. The aim of this study was to determine the ease of frailty testing in a pre-kidney transplant clinic and the resources required to do so. A secondary goal was to better understand the utility of frailty testing when evaluating potential kidney transplant recipients.
METHODS: Frailty testing was conducted at a pre-kidney transplant clinic in three phases using Fried's frailty phenotype (shrinking, exhaustion, low physical activity, slowness, and grip strength).
RESULTS: A total of 132 frailty tests were completed on 128 patients. Frail patients had significantly higher rates of shrinking (26% vs. 8.5%, P < 0.05), exhaustion (82.6% vs. 27.6%, P < 0.05), low physical activity (78.2% vs. 19.0%, P < 0.05), slow walking (60.8% vs. 15.2%, P < 0.05), and grip strength (73.9% vs. 25.7%, P < 0.05). When comparing the listing of frail and non-frail patients for transplant, a significantly lower proportion of frail patients were listed compared to non-frail patients (30.4% vs. 57.6%, P < 0.05). Frailty testing was most complete when an examiner dedicated to frailty testing performed the testing.
CONCLUSIONS: Frailty testing is feasible to complete in a pre-transplant clinic with an appropriate investment in personnel and resources.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Journal of clinical medicine research - 10(2018), 2 vom: 03. Feb., Seite 82-87 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Adlam, Taylor [VerfasserIn] |
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| Links: |
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| Themen: |
Clinical research/practice |
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| Anmerkungen: |
Date Revised 11.03.2022 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.14740/jocmr3203w |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM279808003 |
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| 500 | |a Date Revised 11.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a BACKGROUND: Frailty can be defined as an inflammatory state with a loss of physiologic reserve in multiple systems that manifests as a decreased ability to respond to stressors that ultimately leads to an increased risk of adverse outcomes. The aim of this study was to determine the ease of frailty testing in a pre-kidney transplant clinic and the resources required to do so. A secondary goal was to better understand the utility of frailty testing when evaluating potential kidney transplant recipients | ||
| 520 | |a METHODS: Frailty testing was conducted at a pre-kidney transplant clinic in three phases using Fried's frailty phenotype (shrinking, exhaustion, low physical activity, slowness, and grip strength) | ||
| 520 | |a RESULTS: A total of 132 frailty tests were completed on 128 patients. Frail patients had significantly higher rates of shrinking (26% vs. 8.5%, P < 0.05), exhaustion (82.6% vs. 27.6%, P < 0.05), low physical activity (78.2% vs. 19.0%, P < 0.05), slow walking (60.8% vs. 15.2%, P < 0.05), and grip strength (73.9% vs. 25.7%, P < 0.05). When comparing the listing of frail and non-frail patients for transplant, a significantly lower proportion of frail patients were listed compared to non-frail patients (30.4% vs. 57.6%, P < 0.05). Frailty testing was most complete when an examiner dedicated to frailty testing performed the testing | ||
| 520 | |a CONCLUSIONS: Frailty testing is feasible to complete in a pre-transplant clinic with an appropriate investment in personnel and resources | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Clinical research/practice | |
| 650 | 4 | |a End-stage renal disease | |
| 650 | 4 | |a Frailty testing | |
| 650 | 4 | |a Kidney transplant | |
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| 700 | 1 | |a Kent, Missy |e verfasserin |4 aut | |
| 700 | 1 | |a Malinzak, Lauren |e verfasserin |4 aut | |
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