Elevated CEA is associated with worse survival in recurrent rectal cancer
This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p = 0.005), r-CEA ≥ 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
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| Enthalten in: |
Oncotarget - 8(2017), 62 vom: 01. Dez., Seite 105936-105941 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cho, Won Kyung [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Revised 20.11.2019 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.18632/oncotarget.22511 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM279487185 |
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| 520 | |a This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p = 0.005), r-CEA ≥ 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Park, Won |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, Jeong Il |e verfasserin |4 aut | |
| 700 | 1 | |a Park, Young Suk |e verfasserin |4 aut | |
| 700 | 1 | |a Park, Joon Oh |e verfasserin |4 aut | |
| 700 | 1 | |a Lim, Ho Yeong |e verfasserin |4 aut | |
| 700 | 1 | |a Kang, Won Ki |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Hee Cheol |e verfasserin |4 aut | |
| 700 | 1 | |a Cho, Yong Beom |e verfasserin |4 aut | |
| 700 | 1 | |a Yun, Seong Hyeon |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Woo Yong |e verfasserin |4 aut | |
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