Bilateral acute simultaneous onset anterior uveitis presumed secondary to erlotinib : A report of two cases
PURPOSE: To report two new cases of presumed erlotinib-associated bilateral acute simultaneous-onset anterior uveitis effectively treated with topical steroids.
OBSERVATIONS: Two patients were referred to the uveitis clinic with bilateral acute simultaneous onset, anterior uveitis six weeks after starting the chemotherapeutic agent erlotinib. Frequent topical steroid were started and the inflammation responded swiftly and completely.
CONCLUSIONS AND IMPORTANCE: Bilateral acute simultaneous onset anterior uveitis is a potential side effect associated with erlotinib use that has not been well described. Physicians should be aware of this potential association in patients with recent treatment with erlotinib who complain of blurred vision, photophobia, or redness of the eyes. In some cases, the inflammation responds well to topical therapy and medication can be continued.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:6 |
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| Enthalten in: |
American journal of ophthalmology case reports - 6(2017) vom: 08. Juni, Seite 21-23 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Klein, Kendra A [VerfasserIn] |
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| Links: |
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| Themen: |
Anterior uveitis |
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| Anmerkungen: |
Date Revised 31.03.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.ajoc.2016.09.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM279243197 |
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| 245 | 1 | 0 | |a Bilateral acute simultaneous onset anterior uveitis presumed secondary to erlotinib |b A report of two cases |
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| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a PURPOSE: To report two new cases of presumed erlotinib-associated bilateral acute simultaneous-onset anterior uveitis effectively treated with topical steroids | ||
| 520 | |a OBSERVATIONS: Two patients were referred to the uveitis clinic with bilateral acute simultaneous onset, anterior uveitis six weeks after starting the chemotherapeutic agent erlotinib. Frequent topical steroid were started and the inflammation responded swiftly and completely | ||
| 520 | |a CONCLUSIONS AND IMPORTANCE: Bilateral acute simultaneous onset anterior uveitis is a potential side effect associated with erlotinib use that has not been well described. Physicians should be aware of this potential association in patients with recent treatment with erlotinib who complain of blurred vision, photophobia, or redness of the eyes. In some cases, the inflammation responds well to topical therapy and medication can be continued | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Anterior uveitis | |
| 650 | 4 | |a Epidermal growth factor receptor (EGFR) inhibitor | |
| 650 | 4 | |a Erlotinib | |
| 650 | 4 | |a Non-small cell lung cancer | |
| 650 | 4 | |a Tarceva | |
| 700 | 1 | |a Azzoli, Christopher G |e verfasserin |4 aut | |
| 700 | 1 | |a Rifkin, Lana M |e verfasserin |4 aut | |
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