Clinical-epidemiological study of Bordetella pertussis infection in the Gran Canaria island in the period, 2008-2016
Copyright © 2017 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved..
OBJECTIVE: Describe the epidemiological and clinical pattern of Bordetella pertussis infection (whooping cough) among hospitalised infants less than one year-old in a paediatric hospital in Gran Canaria.
PATIENTS AND METHODS: A retrospective review of the patient hospital records was performed, and recording only those with a microbiological diagnosis of pertussis infection detected using polymerase chain reaction, from January 2008 to December 2016.
RESULTS: A total of 110 patients were identified, of which 105 (95.4%) were less than 6 months-old, and 59.1% were males. The annual incidence of hospital admissions was estimated between 13.7 to 425.0 cases per 100,000 infants <12 months old, with 2peaks in 2011 and 2015. Household members were the main potential sources of infection. Main clinical features were pertussis cough associated with signs of catarrh, cyanosis, and lymphocytosis. Complications occurred in 15.4% of the patients (mainly pneumonia), but the outcome was favourable in all the cases. A lower age and non-vaccination were associated with an increased risk of developing complications (P<.05). Viral co-infection occurred in 31.6% of infants diagnosed with pertussis.
CONCLUSIONS: The incidence of pertussis has increased in the last years in Gran Canaria, with a lower development of complications and mortality rates compared with the previous period. Lower age and non-vaccination status are considered risk factors for developing complications. Vaccination in pregnant women will probably lead to a decline in the incidence in the future, especially in infants younger than 6 months.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:89 |
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| Enthalten in: |
Anales de pediatria - 89(2018), 3 vom: 15. Sept., Seite 170-175 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Estudio clínico-epidemiológico de la infección por Bordetella pertussis en la isla de Gran Canaria en el período 2008-2016 |
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| Beteiligte Personen: |
Iglesias, Laura [VerfasserIn] |
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| Links: |
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| Themen: |
Bordetella pertussis |
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| Anmerkungen: |
Date Completed 28.05.2019 Date Revised 19.09.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.anpedi.2017.10.013 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM278883869 |
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| 245 | 1 | 0 | |a Clinical-epidemiological study of Bordetella pertussis infection in the Gran Canaria island in the period, 2008-2016 |
| 246 | 3 | 3 | |a Estudio clínico-epidemiológico de la infección por Bordetella pertussis en la isla de Gran Canaria en el período 2008-2016 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2017 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a OBJECTIVE: Describe the epidemiological and clinical pattern of Bordetella pertussis infection (whooping cough) among hospitalised infants less than one year-old in a paediatric hospital in Gran Canaria | ||
| 520 | |a PATIENTS AND METHODS: A retrospective review of the patient hospital records was performed, and recording only those with a microbiological diagnosis of pertussis infection detected using polymerase chain reaction, from January 2008 to December 2016 | ||
| 520 | |a RESULTS: A total of 110 patients were identified, of which 105 (95.4%) were less than 6 months-old, and 59.1% were males. The annual incidence of hospital admissions was estimated between 13.7 to 425.0 cases per 100,000 infants <12 months old, with 2peaks in 2011 and 2015. Household members were the main potential sources of infection. Main clinical features were pertussis cough associated with signs of catarrh, cyanosis, and lymphocytosis. Complications occurred in 15.4% of the patients (mainly pneumonia), but the outcome was favourable in all the cases. A lower age and non-vaccination were associated with an increased risk of developing complications (P<.05). Viral co-infection occurred in 31.6% of infants diagnosed with pertussis | ||
| 520 | |a CONCLUSIONS: The incidence of pertussis has increased in the last years in Gran Canaria, with a lower development of complications and mortality rates compared with the previous period. Lower age and non-vaccination status are considered risk factors for developing complications. Vaccination in pregnant women will probably lead to a decline in the incidence in the future, especially in infants younger than 6 months | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Bordetella pertussis | |
| 650 | 4 | |a Coinfección | |
| 650 | 4 | |a Coinfection | |
| 650 | 4 | |a Incidence rate | |
| 650 | 4 | |a Neumonía | |
| 650 | 4 | |a Pneumonia | |
| 650 | 4 | |a Tasa de incidencia | |
| 650 | 4 | |a Tosferina | |
| 650 | 4 | |a Whooping cough | |
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| 700 | 1 | |a Hernández Febles, Melisa |e verfasserin |4 aut | |
| 700 | 1 | |a Colino Gil, Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Eisman Maraver, Alicia |e verfasserin |4 aut | |
| 700 | 1 | |a Pena López, María José |e verfasserin |4 aut | |
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