Influence factors of hepatotoxicity of traditional Chinese medicine preparation products based on multidimensional structure dynamic process
Copyright© by the Chinese Pharmaceutical Association..
Traditional Chinese medicine (TCM) products are the finished products by adopting certain preparation processes according to the profile of the herbs, with Chinese herbs or decoction pieces as the raw materials.Among their adverse reactions to the organs, hepatotoxicity can not be ignored. As a new stage of quality control in TCM, dynamic quality control system of the multidemensional structure process emphasized on the research of the effectiveness and safety, focused on the pretreatment, preparation process,dosage forms and drug delivery methods to control the quality of TCM preparation products and reduce the generation of hepatotoxicity.In this paper, we will start from these factors to discuss the causes of hepatotoxicity underlying drug products and hope to provide the reference for developing low toxicity and high quality modern Chinese medicine products.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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| Enthalten in: |
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 42(2017), 16 vom: 13. Aug., Seite 3031-3035 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Liu, Ying [VerfasserIn] |
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| Links: |
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| Themen: |
Drugs, Chinese Herbal |
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| Anmerkungen: |
Date Completed 19.04.2019 Date Revised 19.04.2019 published: Print Citation Status MEDLINE |
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| doi: |
10.19540/j.cnki.cjcmm.20170714.023 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM278371787 |
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| 520 | |a Traditional Chinese medicine (TCM) products are the finished products by adopting certain preparation processes according to the profile of the herbs, with Chinese herbs or decoction pieces as the raw materials.Among their adverse reactions to the organs, hepatotoxicity can not be ignored. As a new stage of quality control in TCM, dynamic quality control system of the multidemensional structure process emphasized on the research of the effectiveness and safety, focused on the pretreatment, preparation process,dosage forms and drug delivery methods to control the quality of TCM preparation products and reduce the generation of hepatotoxicity.In this paper, we will start from these factors to discuss the causes of hepatotoxicity underlying drug products and hope to provide the reference for developing low toxicity and high quality modern Chinese medicine products | ||
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| 700 | 1 | |a Song, Jie |e verfasserin |4 aut | |
| 700 | 1 | |a Feng, Liang |e verfasserin |4 aut | |
| 700 | 1 | |a Jia, Xiao-Bin |e verfasserin |4 aut | |
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