Discussion on influence factors, mechanism and traditional Chinese medicine pathogenesis of idiosyncratic drug-induced liver injury

Copyright© by the Chinese Pharmaceutical Association..

Idiosyncratic drug-induced liver injury (IDILI) is a kind of unique adverse drug reaction with relative high morbidity compared with other idiosyncratic diseases. Its occurrence, however, has nothing to do with pharmacological effects and clinical dosage of drugs administered, and only a small number of susceptible individuals will suffer from it. Especially to deserve to be mentioned, the proportion of TCM-induced IDILI showed an ascending trend year by year. So in this article, the author has reviewed some facts related with TCM-induced IDILI, including the predisposing causes and occurrence mechanism, and tries to provide reference for the prevention, diagnosis and treatment of TCM-induced IDILI through the analysis of characteristics and research status of TCM-induced IDILI and exploration of the internal relationship between Chinese medicine constitution type and IDILI.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:42

Enthalten in:

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 42(2017), 16 vom: 22. Aug., Seite 3036-3043

Sprache:

Chinesisch

Beteiligte Personen:

Wang, Gang [VerfasserIn]
Liu, Ying [VerfasserIn]
Hou, Xue-Feng [VerfasserIn]
Song, Jie [VerfasserIn]
Qiu, Hui-Hui [VerfasserIn]
Zhong, Qing-Xiang [VerfasserIn]
Jia, Xiao-Bin [VerfasserIn]
Wang, Fu-Jing [VerfasserIn]
Jiang, Nan [VerfasserIn]
Ke, Zhong-Cheng [VerfasserIn]
Feng, Liang [VerfasserIn]

Links:

Volltext

Themen:

Adverse drug reaction
Idiosyncratic drug induced liver injury
Influence factors
Journal Article
Occurrence mechanism
Review

Anmerkungen:

Date Completed 19.04.2019

Date Revised 19.04.2019

published: Print

Citation Status MEDLINE

doi:

10.19540/j.cnki.cjcmm.20170714.014

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM278371728