Autoimmune Thyroiditis : A Case Control Study on a Sample of Egyptian Type I Diabetic Patients
Copyright© by the Egyptian Association of Immunologists..
Type 1 diabetic patients are vulnerable for autoimmune thyroid disease. The incidence of type I Diabetes in Egypt is 8/100000. Undiagnosed thyroid dysfunction impairs metabolic status and increase cardiovascular risks in diabetic patients. Objectives of the study were to underscore autoimmune thyroiditis and thyroid dysfunction on a sample of Egyptian type I diabetes mellitus. One hundred type 1 diabetic subjects without previously known thyroid diseases and 50 controls were included. Physical examination, HbA1c, thyroid profile (TSH, free T3 and free T4), thyroid ultrasound anti-peroxidase and anti-thyroglobulin antibodies were assessed. Autoimmune thyroiditis was detected in 27 % of the patients, and significantly associated with parental consanguinity, familial autoimmune disease and goiter. It is concluded that autoimmune thyroiditis is evident on laboratory assessment of type 1 diabetic patients who were apparently euthyroid. Screening of type I diabetics for thyroid diseases should be done even in absence of clinical evidence for better glycemic control and to improve long term outcome.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2017 |
|---|---|
| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
|---|---|
| Enthalten in: |
The Egyptian journal of immunology - 24(2017), 1 vom: 01. Jan., Seite 119-130 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Bakr, Hoda G [VerfasserIn] |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 25.04.2019 Date Revised 25.04.2019 published: Print Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM277874483 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM277874483 | ||
| 003 | DE-627 | ||
| 005 | 20231225015312.0 | ||
| 007 | tu | ||
| 008 | 231225s2017 xx ||||| 00| ||eng c | ||
| 028 | 5 | 2 | |a pubmed24n0926.xml |
| 035 | |a (DE-627)NLM277874483 | ||
| 035 | |a (NLM)29120584 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Bakr, Hoda G |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Autoimmune Thyroiditis |b A Case Control Study on a Sample of Egyptian Type I Diabetic Patients |
| 264 | 1 | |c 2017 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 25.04.2019 | ||
| 500 | |a Date Revised 25.04.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright© by the Egyptian Association of Immunologists. | ||
| 520 | |a Type 1 diabetic patients are vulnerable for autoimmune thyroid disease. The incidence of type I Diabetes in Egypt is 8/100000. Undiagnosed thyroid dysfunction impairs metabolic status and increase cardiovascular risks in diabetic patients. Objectives of the study were to underscore autoimmune thyroiditis and thyroid dysfunction on a sample of Egyptian type I diabetes mellitus. One hundred type 1 diabetic subjects without previously known thyroid diseases and 50 controls were included. Physical examination, HbA1c, thyroid profile (TSH, free T3 and free T4), thyroid ultrasound anti-peroxidase and anti-thyroglobulin antibodies were assessed. Autoimmune thyroiditis was detected in 27 % of the patients, and significantly associated with parental consanguinity, familial autoimmune disease and goiter. It is concluded that autoimmune thyroiditis is evident on laboratory assessment of type 1 diabetic patients who were apparently euthyroid. Screening of type I diabetics for thyroid diseases should be done even in absence of clinical evidence for better glycemic control and to improve long term outcome | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Autoantibodies |2 NLM | |
| 650 | 7 | |a Thyroid Hormones |2 NLM | |
| 700 | 1 | |a Salem, Ihab M |e verfasserin |4 aut | |
| 700 | 1 | |a Meawed, Takwa E |e verfasserin |4 aut | |
| 700 | 1 | |a Anis, Reham H |e verfasserin |4 aut | |
| 700 | 1 | |a El-Hefnawy, Mohamed H |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Egyptian journal of immunology |d 1995 |g 24(2017), 1 vom: 01. Jan., Seite 119-130 |w (DE-627)NLM097538795 |x 1110-4902 |7 nnns |
| 773 | 1 | 8 | |g volume:24 |g year:2017 |g number:1 |g day:01 |g month:01 |g pages:119-130 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 24 |j 2017 |e 1 |b 01 |c 01 |h 119-130 | ||