Comparison of transcatheter and surgical treatment of paravalvular leak : Results from a 5-year follow-up study
© 2017 Wiley Periodicals, Inc..
OBJECTIVE: This study aimed to compare the efficacy and safety of two different treatments of paravalvular leak (PVL).
BACKGROUND: PVL is a common complication after surgical valve replacement. Re-operation is associated with high mortality, morbidity, and risk of re-leak. Catheter-based repair has emerged as a promising new therapy.
METHODS AND RESULTS: Eighty-seven consecutive patients with symptomatic PVL received either transcatheter (n = 46) or surgical (n = 41) treatment at Shanghai Chest Hospital between January 2009 and December 2015.The procedural and clinical success rates were similar between the transcatheter group and the surgical group (82.6 vs. 90.2%; P = 0.30; and 69.5 vs. 73.0%; P = 0.71, respectively). There were fewer in-hospital total major adverse events in the transcatheter group (56.09 vs. 17.39%; P < 0.001), and transcatheter repair was more cost-effective, with fewer blood transfusions, shorter procedure durations, shorter hospital stays, and less expenditure. However, there were six cases of hemolysis aggravation in the transcatheter group (13.04%). The 5-year overall survival rates after transcatheter and surgical repair were 74.39 and 71.95% (P = 0.45), respectively, and the cardiac-related survival rates were 84.08 and 74.72% (P = 0.19), respectively.
CONCLUSION: Transcatheter and surgical repairs are both effective treatments for selected patients with PVL. And, transcatheter closure seems to be safer and more cost-effective. Nonetheless, this new treatment may be risky for post-procedure hemolysis when unsuitable devices are used.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:94 |
|---|---|
| Enthalten in: |
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions - 94(2019), 2 vom: 01. Aug., Seite E88-E95 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zhang, Youjun [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Comparative Study |
|---|
| Anmerkungen: |
Date Completed 03.08.2020 Date Revised 03.08.2020 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1002/ccd.27371 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM277363713 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM277363713 | ||
| 003 | DE-627 | ||
| 005 | 20231225014039.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/ccd.27371 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0924.xml |
| 035 | |a (DE-627)NLM277363713 | ||
| 035 | |a (NLM)29068133 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Zhang, Youjun |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Comparison of transcatheter and surgical treatment of paravalvular leak |b Results from a 5-year follow-up study |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 03.08.2020 | ||
| 500 | |a Date Revised 03.08.2020 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2017 Wiley Periodicals, Inc. | ||
| 520 | |a OBJECTIVE: This study aimed to compare the efficacy and safety of two different treatments of paravalvular leak (PVL) | ||
| 520 | |a BACKGROUND: PVL is a common complication after surgical valve replacement. Re-operation is associated with high mortality, morbidity, and risk of re-leak. Catheter-based repair has emerged as a promising new therapy | ||
| 520 | |a METHODS AND RESULTS: Eighty-seven consecutive patients with symptomatic PVL received either transcatheter (n = 46) or surgical (n = 41) treatment at Shanghai Chest Hospital between January 2009 and December 2015.The procedural and clinical success rates were similar between the transcatheter group and the surgical group (82.6 vs. 90.2%; P = 0.30; and 69.5 vs. 73.0%; P = 0.71, respectively). There were fewer in-hospital total major adverse events in the transcatheter group (56.09 vs. 17.39%; P < 0.001), and transcatheter repair was more cost-effective, with fewer blood transfusions, shorter procedure durations, shorter hospital stays, and less expenditure. However, there were six cases of hemolysis aggravation in the transcatheter group (13.04%). The 5-year overall survival rates after transcatheter and surgical repair were 74.39 and 71.95% (P = 0.45), respectively, and the cardiac-related survival rates were 84.08 and 74.72% (P = 0.19), respectively | ||
| 520 | |a CONCLUSION: Transcatheter and surgical repairs are both effective treatments for selected patients with PVL. And, transcatheter closure seems to be safer and more cost-effective. Nonetheless, this new treatment may be risky for post-procedure hemolysis when unsuitable devices are used | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a paravalvular leak | |
| 650 | 4 | |a perivalvular leak | |
| 650 | 4 | |a surgical repair | |
| 650 | 4 | |a transcatheter closure | |
| 700 | 1 | |a Pan, Xin |e verfasserin |4 aut | |
| 700 | 1 | |a Qu, Xinkai |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Cheng |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Estella |e verfasserin |4 aut | |
| 700 | 1 | |a Ma, Lan |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Weihua |e verfasserin |4 aut | |
| 700 | 1 | |a Fang, Weiyi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions |d 1999 |g 94(2019), 2 vom: 01. Aug., Seite E88-E95 |w (DE-627)NLM101487487 |x 1522-726X |7 nnns |
| 773 | 1 | 8 | |g volume:94 |g year:2019 |g number:2 |g day:01 |g month:08 |g pages:E88-E95 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/ccd.27371 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 94 |j 2019 |e 2 |b 01 |c 08 |h E88-E95 | ||