Influenza vaccination of patients with solid tumours during chemotherapy : efficacy and safety

- Adult patients with solid tumours receiving chemotherapy have reduced immunity against infections and are at increased risk of influenza infection and its complications. However, many of said patients are not vaccinated for influenza.- Limited observational research in this patient group has given some indication of the protective effects of the influenza vaccine on clinical outcome measures.- Serological studies have shown that the antibody response following influenza vaccination is often less pronounced in patients with solid tumours compared to healthy individuals. Nonetheless, in most cases a timely protective antibody response can be achieved.- The inactivated influenza vaccine is safe in immunosuppressed patients, irrespective of the moment at which it is administered. Side-effects are similar, both in nature and number, to those seen in healthy individuals.- Influenza vaccination can be offered to all adult patients with solid tumours, preferably before chemotherapy is commenced. Vaccination during chemotherapy, however, usually also generates sufficient vaccination response and can reduce the risk of influenza-related complications. Therefore, chemotherapy should not preclude patients from being administered the influenza vaccine.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:161

Enthalten in:

Nederlands tijdschrift voor geneeskunde - 161(2017) vom: 08., Seite D2066

Sprache:

Niederländisch

Weiterer Titel:

Griepvaccinatie tijdens chemotherapie bij patiënten met solide tumoren

Beteiligte Personen:

Vollaard, A M [VerfasserIn]
Schreuder, I [VerfasserIn]
Slok-Raijmakers, L [VerfasserIn]
Opstelten, W [VerfasserIn]
Rimmelzwaan, G F [VerfasserIn]
Gelderblom, A J [VerfasserIn]

Themen:

English Abstract
Journal Article

Anmerkungen:

Date Completed 27.06.2018

Date Revised 07.08.2018

published: Print

Citation Status PubMed-not-MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM276963466