Computerized Bone Age Estimation Using Deep Learning Based Program : Evaluation of the Accuracy and Efficiency

OBJECTIVE: The purpose of this study is to evaluate the accuracy and efficiency of a new automatic software system for bone age assessment and to validate its feasibility in clinical practice.

MATERIALS AND METHODS: A Greulich-Pyle method-based deep-learning technique was used to develop the automatic software system for bone age determination. Using this software, bone age was estimated from left-hand radiographs of 200 patients (3-17 years old) using first-rank bone age (software only), computer-assisted bone age (two radiologists with software assistance), and Greulich-Pyle atlas-assisted bone age (two radiologists with Greulich-Pyle atlas assistance only). The reference bone age was determined by the consensus of two experienced radiologists.

RESULTS: First-rank bone ages determined by the automatic software system showed a 69.5% concordance rate and significant correlations with the reference bone age (r = 0.992; p < 0.001). Concordance rates increased with the use of the automatic software system for both reviewer 1 (63.0% for Greulich-Pyle atlas-assisted bone age vs 72.5% for computer-assisted bone age) and reviewer 2 (49.5% for Greulich-Pyle atlas-assisted bone age vs 57.5% for computer-assisted bone age). Reading times were reduced by 18.0% and 40.0% for reviewers 1 and 2, respectively.

CONCLUSION: Automatic software system showed reliably accurate bone age estimations and appeared to enhance efficiency by reducing reading times without compromising the diagnostic accuracy.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:209

Enthalten in:

AJR. American journal of roentgenology - 209(2017), 6 vom: 17. Dez., Seite 1374-1380

Sprache:

Englisch

Beteiligte Personen:

Kim, Jeong Rye [VerfasserIn]
Shim, Woo Hyun [VerfasserIn]
Yoon, Hee Mang [VerfasserIn]
Hong, Sang Hyup [VerfasserIn]
Lee, Jin Seong [VerfasserIn]
Cho, Young Ah [VerfasserIn]
Kim, Sangki [VerfasserIn]

Links:

Volltext

Themen:

Bone age
Children
Deep learning
Journal Article
Neural network model

Anmerkungen:

Date Completed 05.12.2017

Date Revised 10.12.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2214/AJR.17.18224

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM275690911