Control of multidrug-resistant Acinetobacter baumannii in Hong Kong : Role of environmental surveillance in communal areas after a hospital outbreak
Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved..
BACKGROUND: Environmental reservoir is an important source of multidrug-resistant Acinetobacter baumannii (MRAB) outbreaks. The role of postoutbreak environmental surveillance for guiding sustained infection control effort has not been examined.
METHODS: Enhanced environmental disinfection and regular environmental surveillance of ward communal areas after an outbreak were performed in a university-affiliated hospital. To assess the usefulness of environmental culture in predicting patients with MRAB, weekly surveillance of communal areas was continued for 3 months after the outbreak in intervention wards. The incidence of MRAB in intervention and nonintervention wards (control) was compared, whereas the other infection control measures remained identical.
RESULTS: Postoutbreak weekly surveillance of communal areas showed that identification of newly diagnosed MRAB patients was significantly correlated with preceding environmental contamination with MRAB (P = .001). The incidence of nosocomial MRAB infection was significantly lower in the intervention compared with nonintervention wards (0.55 vs 2.28 per 1,000 patient days, respectively; P = .04). All MRAB isolated from the environmental and patients' samples belonged to multilocus sequence typing ST457 and were blaOXA23-like positive.
CONCLUSIONS: Environmental surveillance may serve as a surrogate marker for the presence of MRAB carriers. Implementation of timely infection control measures should be guided by environmental culture for MRAB to minimize the risk of MRAB outbreak.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
American journal of infection control - 46(2018), 1 vom: 01. Jan., Seite 60-66 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cheng, Vincent C C [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Bacterial Agents |
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| Anmerkungen: |
Date Completed 14.03.2019 Date Revised 14.03.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ajic.2017.07.010 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM275644685 |
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| 100 | 1 | |a Cheng, Vincent C C |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Control of multidrug-resistant Acinetobacter baumannii in Hong Kong |b Role of environmental surveillance in communal areas after a hospital outbreak |
| 264 | 1 | |c 2018 | |
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| 500 | |a Date Completed 14.03.2019 | ||
| 500 | |a Date Revised 14.03.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Environmental reservoir is an important source of multidrug-resistant Acinetobacter baumannii (MRAB) outbreaks. The role of postoutbreak environmental surveillance for guiding sustained infection control effort has not been examined | ||
| 520 | |a METHODS: Enhanced environmental disinfection and regular environmental surveillance of ward communal areas after an outbreak were performed in a university-affiliated hospital. To assess the usefulness of environmental culture in predicting patients with MRAB, weekly surveillance of communal areas was continued for 3 months after the outbreak in intervention wards. The incidence of MRAB in intervention and nonintervention wards (control) was compared, whereas the other infection control measures remained identical | ||
| 520 | |a RESULTS: Postoutbreak weekly surveillance of communal areas showed that identification of newly diagnosed MRAB patients was significantly correlated with preceding environmental contamination with MRAB (P = .001). The incidence of nosocomial MRAB infection was significantly lower in the intervention compared with nonintervention wards (0.55 vs 2.28 per 1,000 patient days, respectively; P = .04). All MRAB isolated from the environmental and patients' samples belonged to multilocus sequence typing ST457 and were blaOXA23-like positive | ||
| 520 | |a CONCLUSIONS: Environmental surveillance may serve as a surrogate marker for the presence of MRAB carriers. Implementation of timely infection control measures should be guided by environmental culture for MRAB to minimize the risk of MRAB outbreak | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Environmental surveillance | |
| 650 | 4 | |a Multidrug-resistant Acinetobacter baumannii | |
| 650 | 4 | |a Outbreak | |
| 650 | 7 | |a Anti-Bacterial Agents |2 NLM | |
| 700 | 1 | |a Wong, Shuk-Ching |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Jonathan H K |e verfasserin |4 aut | |
| 700 | 1 | |a So, Simon Y C |e verfasserin |4 aut | |
| 700 | 1 | |a Wong, Sally C Y |e verfasserin |4 aut | |
| 700 | 1 | |a Ho, Pak-Leung |e verfasserin |4 aut | |
| 700 | 1 | |a Yuen, Kwok-Yung |e verfasserin |4 aut | |
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