Recent advances in biocompatible semiconductor nanocrystals for immunobiological applications

Copyright © 2017 Elsevier B.V. All rights reserved..

Quantum confinement in inorganic semiconductor nanocrystals produces brightly luminescent nanoparticles endowed with unique photo-physical properties, such as tunable optical properties. These have found widespread applications in nanotechnology. The ability to render such nanostructures biocompatible, while maintaining their tunable radiation in the visible range of the electromagnetic spectrum, renders them appropriate for bio-applications. Promising in vitro and in vivo diagnostic applications have been demonstrated, such as fluorescence-based detection of biological interactions, single molecule tracking, multiplexing and immunoassaying. In particular, these fluorescent inorganic semiconductor nanocrystals, generally known as quantum dots, have the potential of remarkable immunobiological applications. This review focuses on the current status of biocompatible quantum dots and their applications in immunobiology - immunosensing, immunofluorescent imaging and immunotherapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:159

Enthalten in:

Colloids and surfaces. B, Biointerfaces - 159(2017) vom: 01. Nov., Seite 644-654

Sprache:

Englisch

Beteiligte Personen:

Nanda, Sitansu Sekhar [VerfasserIn]
Kim, Min Jik [VerfasserIn]
Kim, Kwangmeyung [VerfasserIn]
Papaefthymiou, Georgia C [VerfasserIn]
Selvan, Subramanian Tamil [VerfasserIn]
Yi, Dong Kee [VerfasserIn]

Links:

Volltext

Themen:

Immunoassay
Immunofluorescent imaging
Immunosensor
Immunotherapy
Journal Article
Quantum dots
Review

Anmerkungen:

Date Completed 09.07.2018

Date Revised 09.07.2018

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.colsurfb.2017.08.026

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM275374955