In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives
Copyright © 2017 American Society for Microbiology..
The in vitro activities of novel azoles compared to those of five antifungal drugs against clinical (n = 28) and environmental (n = 102) isolates of black mold and melanized yeast were determined. Luliconazole and lanoconazole had the lowest geometric mean MICs, followed by efinaconazole, against tested isolates compared to the other drugs. Therefore, it appears that these new imidazole and triazole drugs are promising candidates for the treatment of infections due to melanized fungi and their relatives.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2017 |
---|---|
Erschienen: |
2017 |
Enthalten in: |
Zur Gesamtaufnahme - volume:61 |
---|---|
Enthalten in: |
Antimicrobial agents and chemotherapy - 61(2017), 11 vom: 30. Nov. |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Shokoohi, Gholam Reza [VerfasserIn] |
---|
Links: |
---|
Themen: |
4E7858311F |
---|
Anmerkungen: |
Date Completed 26.06.2018 Date Revised 02.12.2018 published: Electronic-Print Citation Status MEDLINE |
---|
doi: |
10.1128/AAC.00635-17 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM275205576 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM275205576 | ||
003 | DE-627 | ||
005 | 20231225005146.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2017 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1128/AAC.00635-17 |2 doi | |
028 | 5 | 2 | |a pubmed24n0917.xml |
035 | |a (DE-627)NLM275205576 | ||
035 | |a (NLM)28848012 | ||
035 | |a (PII)e00635-17 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Shokoohi, Gholam Reza |e verfasserin |4 aut | |
245 | 1 | 0 | |a In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives |
264 | 1 | |c 2017 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 26.06.2018 | ||
500 | |a Date Revised 02.12.2018 | ||
500 | |a published: Electronic-Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2017 American Society for Microbiology. | ||
520 | |a The in vitro activities of novel azoles compared to those of five antifungal drugs against clinical (n = 28) and environmental (n = 102) isolates of black mold and melanized yeast were determined. Luliconazole and lanoconazole had the lowest geometric mean MICs, followed by efinaconazole, against tested isolates compared to the other drugs. Therefore, it appears that these new imidazole and triazole drugs are promising candidates for the treatment of infections due to melanized fungi and their relatives | ||
650 | 4 | |a Comparative Study | |
650 | 4 | |a Journal Article | |
650 | 4 | |a MIC | |
650 | 4 | |a efinaconazole | |
650 | 4 | |a in vitro | |
650 | 4 | |a lanoconazole | |
650 | 4 | |a luliconazole | |
650 | 4 | |a melanized fungi | |
650 | 7 | |a Antifungal Agents |2 NLM | |
650 | 7 | |a Imidazoles |2 NLM | |
650 | 7 | |a Triazoles |2 NLM | |
650 | 7 | |a latoconazole |2 NLM | |
650 | 7 | |a 4E7858311F |2 NLM | |
650 | 7 | |a efinaconazole |2 NLM | |
650 | 7 | |a J82SB7FXWB |2 NLM | |
650 | 7 | |a luliconazole |2 NLM | |
650 | 7 | |a RE91AN4S8G |2 NLM | |
700 | 1 | |a Badali, Hamid |e verfasserin |4 aut | |
700 | 1 | |a Mirhendi, Hossein |e verfasserin |4 aut | |
700 | 1 | |a Ansari, Saham |e verfasserin |4 aut | |
700 | 1 | |a Rezaei-Matehkolaei, Ali |e verfasserin |4 aut | |
700 | 1 | |a Ahmadi, Bahram |e verfasserin |4 aut | |
700 | 1 | |a Vaezi, Afsane |e verfasserin |4 aut | |
700 | 1 | |a Alshahni, Mohamed Mahdi |e verfasserin |4 aut | |
700 | 1 | |a Makimura, Koichi |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Antimicrobial agents and chemotherapy |d 1972 |g 61(2017), 11 vom: 30. Nov. |w (DE-627)NLM000026506 |x 1098-6596 |7 nnns |
773 | 1 | 8 | |g volume:61 |g year:2017 |g number:11 |g day:30 |g month:11 |
856 | 4 | 0 | |u http://dx.doi.org/10.1128/AAC.00635-17 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 61 |j 2017 |e 11 |b 30 |c 11 |