Factors affecting the survival of transplants from donors after prehospital cardiac death
OBJECTIVES: To evaluate factors that influence the survival of transplanted organs from donors after prehospital cardiac death.
MATERIAL AND METHODS: Retrospective observational study of data collected from hospital emergency service records. Information included prehospital cardiac deaths evaluated as donors as well as patients who received transplants.
RESULTS: Two hundred cases from 2008 through 2011 were studied. Sixty-nine potential donors (34.5%) were rejected. Three hundred organs were extracted from the remaining 131 donor cases, to yield a mean (SD) of 2.32 (0.83) transplanted organs/donor or 1.52 (1.29) organs/potential donor. One hundred fifty-two potential donors (76%) were treated with mechanical cardiopumps during transport. We detected no significant differences between cases transported with manual chest compressions and cases treated with cardiopumps regarding age (40.1 vs 43.5 years, P=.06), responder arrival times (13 min 54 s vs 12 min 54 s, P=.45), or transport times (1 h 27 min vs 1 h 32 min). However, case transported with manual chest compressions yielded significantly more kidneys (mean, 1.96/potential donor) than those transported with cardiopump compressions (mean, 1.38/potential donor) (P=.008). Eleven of the 229 kidneys harvested (4%) were not transplanted. The median (interquartile range) serum creatinine concentrations after kidney transplants at 6 and 12 months, respectively, were 1.37 (1.10-1.58) mg/dL and 1.43 (1.11-1.80) mg/dL.
CONCLUSION: Our findings suggest that the use of a cardiopump reduces donor recruitment. Long-term creatinine levels are similar after transplantation of kidneys from donors transported with a cardiopump or with manual compressions.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
|---|---|
| Enthalten in: |
Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias - 29(2017), 3 vom: 21. Juni, Seite 167-172 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Factores que influyen en la evolución de los injertos de donantes tras muerte cardiaca extrahospitalaria |
|---|
| Beteiligte Personen: |
Mateos Rodríguez, Alonso Antonio [VerfasserIn] |
|---|
| Themen: |
AYI8EX34EU |
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| Anmerkungen: |
Date Completed 10.07.2018 Date Revised 29.08.2018 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM274983141 |
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| 245 | 1 | 0 | |a Factors affecting the survival of transplants from donors after prehospital cardiac death |
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| 500 | |a Date Completed 10.07.2018 | ||
| 500 | |a Date Revised 29.08.2018 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: To evaluate factors that influence the survival of transplanted organs from donors after prehospital cardiac death | ||
| 520 | |a MATERIAL AND METHODS: Retrospective observational study of data collected from hospital emergency service records. Information included prehospital cardiac deaths evaluated as donors as well as patients who received transplants | ||
| 520 | |a RESULTS: Two hundred cases from 2008 through 2011 were studied. Sixty-nine potential donors (34.5%) were rejected. Three hundred organs were extracted from the remaining 131 donor cases, to yield a mean (SD) of 2.32 (0.83) transplanted organs/donor or 1.52 (1.29) organs/potential donor. One hundred fifty-two potential donors (76%) were treated with mechanical cardiopumps during transport. We detected no significant differences between cases transported with manual chest compressions and cases treated with cardiopumps regarding age (40.1 vs 43.5 years, P=.06), responder arrival times (13 min 54 s vs 12 min 54 s, P=.45), or transport times (1 h 27 min vs 1 h 32 min). However, case transported with manual chest compressions yielded significantly more kidneys (mean, 1.96/potential donor) than those transported with cardiopump compressions (mean, 1.38/potential donor) (P=.008). Eleven of the 229 kidneys harvested (4%) were not transplanted. The median (interquartile range) serum creatinine concentrations after kidney transplants at 6 and 12 months, respectively, were 1.37 (1.10-1.58) mg/dL and 1.43 (1.11-1.80) mg/dL | ||
| 520 | |a CONCLUSION: Our findings suggest that the use of a cardiopump reduces donor recruitment. Long-term creatinine levels are similar after transplantation of kidneys from donors transported with a cardiopump or with manual compressions | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Donación tras muerte cardiaca | |
| 650 | 4 | |a Emergency health services | |
| 650 | 4 | |a Organ donation after cardiac death | |
| 650 | 4 | |a Servicios de emergencias | |
| 650 | 4 | |a Transplants | |
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| 700 | 1 | |a Del Río Gallegos, Francisco |e verfasserin |4 aut | |
| 700 | 1 | |a Coll, Elisabeth |e verfasserin |4 aut | |
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