Compliancy of pre-exposure prophylaxis for HIV infection in men who have sex with men in Chengdu
Objective: To evaluate the compliancy of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Chengdu, Sichuan province, and explore the influencing factors. Methods: From 1 July 2013 to 30 September 2015, a random, open, multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu. The MSM were divided into 3 groups randomly, i.e. daily group, intermittent group (before and after exposure) and control group. Clinical follow-up and questionnaire survey were carried out every 3 months. Their PrEP compliances were evaluated respectively and multivariate logistic regression analysis was conducted to identify the related factors. Results: A total of 141 MSM were surveyed, in whom 59(41.8%) had good PrEP compliancy. The PrEP compliancy rate was 69.0% in daily group, higher than that in intermittent group (14.3%), the difference had significance (χ(2)=45.29,P<0.001). Multivariate logistic analysis indicated that type of PrEP was the influencing factors of PrEP compliancy. Compared with daily group, the intermittent group had worse PrEP compliancy (OR=0.07, 95%CI: 0.03-0.16). Conclusion: The PrEP compliance of the MSM in this study was poor, the compliancy would be influenced by the type of PrEP.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:38 |
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| Enthalten in: |
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 38(2017), 5 vom: 10. Mai, Seite 643-645 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Xu, J Y [VerfasserIn] |
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| Links: |
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| Themen: |
AIDS |
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| Anmerkungen: |
Date Completed 04.09.2017 Date Revised 02.12.2018 published: Print Citation Status MEDLINE |
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| doi: |
10.3760/cma.j.issn.0254-6450.2017.05.017 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM273290479 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Objective: To evaluate the compliancy of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Chengdu, Sichuan province, and explore the influencing factors. Methods: From 1 July 2013 to 30 September 2015, a random, open, multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu. The MSM were divided into 3 groups randomly, i.e. daily group, intermittent group (before and after exposure) and control group. Clinical follow-up and questionnaire survey were carried out every 3 months. Their PrEP compliances were evaluated respectively and multivariate logistic regression analysis was conducted to identify the related factors. Results: A total of 141 MSM were surveyed, in whom 59(41.8%) had good PrEP compliancy. The PrEP compliancy rate was 69.0% in daily group, higher than that in intermittent group (14.3%), the difference had significance (χ(2)=45.29,P<0.001). Multivariate logistic analysis indicated that type of PrEP was the influencing factors of PrEP compliancy. Compared with daily group, the intermittent group had worse PrEP compliancy (OR=0.07, 95%CI: 0.03-0.16). Conclusion: The PrEP compliance of the MSM in this study was poor, the compliancy would be influenced by the type of PrEP | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a AIDS | |
| 650 | 4 | |a Compliancy | |
| 650 | 4 | |a Men who have sex with men | |
| 650 | 4 | |a Pre-exposure prophylaxis | |
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| 700 | 1 | |a Zhang, J Y |e verfasserin |4 aut | |
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