A pooled analysis of combined liver and inferior vena cava resection for hepatic malignancy

Copyright © 2017 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd. All rights reserved..

BACKGROUND: Limited data are currently available to address the safety and efficacy of combined resection of the liver and inferior vena cava (IVC) for hepatic malignancies.

METHODS: A systematic review was performed to identify relevant studies. Pooled individual data were examined for the clinical outcome of combined resection of the liver and IVC for hepatic malignancies.

RESULTS: A total of 258 patients were described in 38 articles eligible for inclusion. Resections were performed for colorectal liver metastasis (CLM) [n = 128 (50%)], intrahepatic cholangiocarcinoma (ICC) [n = 51 (20%)], hepatocellular carcinoma (HCC) [n = 48 (19%)], and other pathologies [n = 31 (11%)]. There were 14 (5%) perioperative deaths. The median survival duration was 34 months, and the 1-, 3- and 5-year overall survival (OS) rate was 79%, 46% and 33%, respectively. The 5-year OS rate was 26% for CLM, 37% for ICC, and 30% for HCC.

CONCLUSION: Combined resection of the liver and IVC for hepatic malignancies is safe and applicable, and offers acceptable survival outcomes.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

HPB : the official journal of the International Hepato Pancreato Biliary Association - 19(2017), 9 vom: 08. Sept., Seite 768-774

Sprache:

Englisch

Beteiligte Personen:

Zhou, Yanming [VerfasserIn]
Wu, Lupeng [VerfasserIn]
Xu, Dong [VerfasserIn]
Wan, Tao [VerfasserIn]
Si, Xiaoying [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Review
Systematic Review

Anmerkungen:

Date Completed 22.05.2018

Date Revised 02.12.2018

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.hpb.2017.05.008

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM273233882