Oral ulcer activity in Behcet's disease : Poor medication adherence is an underestimated risk factor
OBJECTIVE: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behçet's disease (BD) patients.
MATERIAL AND METHODS: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5±10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of "0" to "8" with high scores indicating better adherence. Low adherence was defined as <6 points on MMAS-8.
RESULTS: Over half of the group had active oral ulcers (n=219, 66.4%) within the month preceding the visit. The number of oral ulcers was significantly higher in female patients with low medication adherence (2.39±3.24) than in the rest of the female group (1.28±2.05; p=0.023). Although a similar trend was also observed in male patients (2.14±3.3 vs. 1.81±2.31), a significant relationship was not observed (p=0.89). The frequency of medication intake per day was lower in patients with high medication adherence than in the rest of the study group (p=0.04).
CONCLUSION: Low medication adherence is a hidden risk factor in the management of BD. Poor adherence was associated with oral ulcer activity in female BD patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:4 |
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| Enthalten in: |
European journal of rheumatology - 4(2017), 2 vom: 01. Juni, Seite 109-112 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Mumcu, Gonca [VerfasserIn] |
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| Links: |
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| Themen: |
Behçet’s disease |
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| Anmerkungen: |
Date Revised 26.03.2024 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.5152/eurjrheum.2017.160094 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM273166921 |
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| 500 | |a Date Revised 26.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a OBJECTIVE: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behçet's disease (BD) patients | ||
| 520 | |a MATERIAL AND METHODS: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5±10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of "0" to "8" with high scores indicating better adherence. Low adherence was defined as <6 points on MMAS-8 | ||
| 520 | |a RESULTS: Over half of the group had active oral ulcers (n=219, 66.4%) within the month preceding the visit. The number of oral ulcers was significantly higher in female patients with low medication adherence (2.39±3.24) than in the rest of the female group (1.28±2.05; p=0.023). Although a similar trend was also observed in male patients (2.14±3.3 vs. 1.81±2.31), a significant relationship was not observed (p=0.89). The frequency of medication intake per day was lower in patients with high medication adherence than in the rest of the study group (p=0.04) | ||
| 520 | |a CONCLUSION: Low medication adherence is a hidden risk factor in the management of BD. Poor adherence was associated with oral ulcer activity in female BD patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Behçet’s disease | |
| 650 | 4 | |a Medication adherence | |
| 650 | 4 | |a oral ulcer | |
| 700 | 1 | |a Alibaz-Öner, Fatma |e verfasserin |4 aut | |
| 700 | 1 | |a Öner, Sibel Yılmaz |e verfasserin |4 aut | |
| 700 | 1 | |a Özen, Gülsen |e verfasserin |4 aut | |
| 700 | 1 | |a Atagündüz, Pamir |e verfasserin |4 aut | |
| 700 | 1 | |a İnanç, Nevsun |e verfasserin |4 aut | |
| 700 | 1 | |a Köksal, Leyla |e verfasserin |4 aut | |
| 700 | 1 | |a Ergun, Tülin |e verfasserin |4 aut | |
| 700 | 1 | |a Direskeneli, Haner |e verfasserin |4 aut | |
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