Prevalence of abnormal lactose breath hydrogen tests in children with functional abdominal pain
OBJECTIVES: The study was undertaken to determine the prevalence of abnormal lactose breath hydrogen test in children with non-organic chronic abdominal pain.
METHODS: Children with chronic abdominal pain were examined and investigated for organic causes. All children without a known organic cause underwent lactose and glucose breath hydrogen test. After a standard dose of 2 g/kg of lactose to a maximum of 50 g, hydrogen in breath was measured at 15 min intervals for 3 h. A rise of 20 ppm above baseline was considered suggestive of lactose malabsorption.
RESULTS: Of 108 children screened, organic causes were found in 46 children. Sixty-two patients without any organic cause underwent hydrogen breath test. Lactose hydrogen breath test (HBT) was positive in 36 of 62 (58%), while 11 (17%) had positive HBT with glucose suggestive of small intestinal bacterial overgrowth (SIBO). Twenty out of 34 (59%) improved on lactose free diet while 8 out of 11 (72%) children of SIBO improved on antibiotics.
CONCLUSIONS: Lactose malabsorption was seen in 58% of children with non-organic chronic abdominal pain.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
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| Enthalten in: |
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 36(2017), 3 vom: Mai, Seite 179-183 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Garg, Neha [VerfasserIn] |
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| Links: |
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| Themen: |
7YNJ3PO35Z |
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| Anmerkungen: |
Date Completed 17.11.2017 Date Revised 26.11.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s12664-017-0750-8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM272693618 |
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| 245 | 1 | 0 | |a Prevalence of abnormal lactose breath hydrogen tests in children with functional abdominal pain |
| 264 | 1 | |c 2017 | |
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| 500 | |a Date Completed 17.11.2017 | ||
| 500 | |a Date Revised 26.11.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: The study was undertaken to determine the prevalence of abnormal lactose breath hydrogen test in children with non-organic chronic abdominal pain | ||
| 520 | |a METHODS: Children with chronic abdominal pain were examined and investigated for organic causes. All children without a known organic cause underwent lactose and glucose breath hydrogen test. After a standard dose of 2 g/kg of lactose to a maximum of 50 g, hydrogen in breath was measured at 15 min intervals for 3 h. A rise of 20 ppm above baseline was considered suggestive of lactose malabsorption | ||
| 520 | |a RESULTS: Of 108 children screened, organic causes were found in 46 children. Sixty-two patients without any organic cause underwent hydrogen breath test. Lactose hydrogen breath test (HBT) was positive in 36 of 62 (58%), while 11 (17%) had positive HBT with glucose suggestive of small intestinal bacterial overgrowth (SIBO). Twenty out of 34 (59%) improved on lactose free diet while 8 out of 11 (72%) children of SIBO improved on antibiotics | ||
| 520 | |a CONCLUSIONS: Lactose malabsorption was seen in 58% of children with non-organic chronic abdominal pain | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Hydrogen breath tests | |
| 650 | 4 | |a Recurrent acute pancreatitis | |
| 650 | 4 | |a Small intestinal bacterial overgrowth | |
| 650 | 7 | |a Hydrogen |2 NLM | |
| 650 | 7 | |a 7YNJ3PO35Z |2 NLM | |
| 650 | 7 | |a Lactose |2 NLM | |
| 650 | 7 | |a J2B2A4N98G |2 NLM | |
| 700 | 1 | |a Basu, Srikanta |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Preeti |e verfasserin |4 aut | |
| 700 | 1 | |a Kumar, Ruchika |e verfasserin |4 aut | |
| 700 | 1 | |a Sharma, Lokesh |e verfasserin |4 aut | |
| 700 | 1 | |a Kumar, Praveen |e verfasserin |4 aut | |
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