Structures of the K35 and K15 capsular polysaccharides of Acinetobacter baumannii LUH5535 and LUH5554 containing amino and diamino uronic acids
Copyright © 2017 Elsevier Ltd. All rights reserved..
Capsular polysaccharides were isolated from A. baumannii LUH5535 (K35 CPS) and LUH5554 (K15 CPS) and studied by 1D and 2D 1H and 13C NMR spectroscopy. The CPSs were found to consist of linear tetrasaccharide repeats (K units) containing 2-acetamido-2-deoxy-d-galacturonic acid (K35) or 2,3-diacetamido-2,3-deoxy-d-glucuronic acid (K15) and 2,4-diacetamido-2,4,6-trideoxy-d-glucose (both CPSs). The K35 unit includes three O-acetyl groups on different GalNAcA residues. A. baumannii LUH5535 and LUH5554 carry the KL35 and KL15 gene clusters, respectively, and putatively assigned functions of genes in these clusters were consistent with the CPS structures established.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2017 |
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Erschienen: |
2017 |
Enthalten in: |
Zur Gesamtaufnahme - volume:448 |
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Enthalten in: |
Carbohydrate research - 448(2017) vom: 07. Aug., Seite 28-34 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Shashkov, Alexander S [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 22.03.2018 Date Revised 22.03.2018 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.carres.2017.05.017 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM272585548 |
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245 | 1 | 0 | |a Structures of the K35 and K15 capsular polysaccharides of Acinetobacter baumannii LUH5535 and LUH5554 containing amino and diamino uronic acids |
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500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2017 Elsevier Ltd. All rights reserved. | ||
520 | |a Capsular polysaccharides were isolated from A. baumannii LUH5535 (K35 CPS) and LUH5554 (K15 CPS) and studied by 1D and 2D 1H and 13C NMR spectroscopy. The CPSs were found to consist of linear tetrasaccharide repeats (K units) containing 2-acetamido-2-deoxy-d-galacturonic acid (K35) or 2,3-diacetamido-2,3-deoxy-d-glucuronic acid (K15) and 2,4-diacetamido-2,4,6-trideoxy-d-glucose (both CPSs). The K35 unit includes three O-acetyl groups on different GalNAcA residues. A. baumannii LUH5535 and LUH5554 carry the KL35 and KL15 gene clusters, respectively, and putatively assigned functions of genes in these clusters were consistent with the CPS structures established | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a 2,3-Diacetamido-2,3-deoxy-d-glucuronic acid | |
650 | 4 | |a 2,4-Diacetamido-2,4,6-trideoxy-d-glucose | |
650 | 4 | |a 2-Acetamido-2-deoxy-d-galacturonic acid | |
650 | 4 | |a Acinetobacter baumannii | |
650 | 4 | |a Capsular polysaccharide structure | |
650 | 4 | |a K locus | |
650 | 7 | |a Polysaccharides, Bacterial |2 NLM | |
650 | 7 | |a Uronic Acids |2 NLM | |
700 | 1 | |a Liu, Bin |e verfasserin |4 aut | |
700 | 1 | |a Kenyon, Johanna J |e verfasserin |4 aut | |
700 | 1 | |a Popova, Anastasiya V |e verfasserin |4 aut | |
700 | 1 | |a Shneider, Mikhail M |e verfasserin |4 aut | |
700 | 1 | |a Senchenkova, Sof'ya N |e verfasserin |4 aut | |
700 | 1 | |a Arbatsky, Nikolay P |e verfasserin |4 aut | |
700 | 1 | |a Miroshnikov, Konstantin A |e verfasserin |4 aut | |
700 | 1 | |a Wang, Lei |e verfasserin |4 aut | |
700 | 1 | |a Knirel, Yuriy A |e verfasserin |4 aut | |
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