Anesthesia recovery comparison between remifentanil-propofol and remifentanil-desflurane guided by Bispectral Index® monitoring

Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved..

BACKGROUND AND OBJECTIVES: There is a strong demand for fast and predictable anesthesia recovery with few side effects. Choice of the hypnotic agent could impact on that. This study investigated the differences between recoveries after remifentanil-propofol and remifentanil-desflurane anesthesias guided by bispectral index (BIS®).

METHODS: Forty patients were randomly assigned into 2 groups according to the anesthesia technique applied: remifentanil-propofol (REM-PRO) and remifentanil-desflurane (REM-DES). After the discontinuation of the anesthetics, the times to extubation, to obey commands and to recover the airway protection reflex were recorted. In the post-anesthetic recovery room (PACU) it was recorded the occurrence of nausea and vomiting (PONV), scores of Ramsay sedation scale and of numeric pain scale (NPS), morphine dose and length of stay in the unit.

RESULTS: Data from 38 patients were analyzed: 18 from REM-PRO and 20 from REM-DES group. Anesthesia times were similar (REM-PRO=193min, SD 79.9 vs. 175.7min, SD 87.9 REM-DES; p=0.5). REM-DES had shorter times than REM-PRO group: time to follow command (8.5min; SD 3.0 vs. 5.6min; SD 2.5; p=0.0) and extubation time (6.2 minutes; 3.1-8.5 vs. 9.5 minutes; 4.9-14.4; p=0.0). Times to recover airway protective reflex were similar: 16 patients from REM-PRO (88.9%) restored the airway protective reflex 2min after extubation vs. 17 from REM-DES (89.5%); and 2 patients from REM-PRO (11.1%) vs. 2 from REM-DES (10.5%) 6min after extubation, p=1. Ramsay sedation score, NPS, PONV incidents, morphine dose and PACU stay of length PACU were also similar.

CONCLUSION: Remifentanil-desflurane-based anesthesia has a faster extubation time and to follow command than remifentanil-propofol-based anesthesia when both guided by BIS®.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:67

Enthalten in:

Revista brasileira de anestesiologia - 67(2017), 5 vom: 14. Sept., Seite 500-507

Sprache:

Portugiesisch

Weiterer Titel:

Comparação da recuperação pós-anestésica entre remifentanil‐propofol e remifentanil‐desflurano guiada pela monitoração do Índice Bispectral®

Beteiligte Personen:

Rocha, Raphael Grossi [VerfasserIn]
Almeida, Eduardo Giarola [VerfasserIn]
Carneiro, Lara Moreira Mendes [VerfasserIn]
Almeida, Natália Farias de [VerfasserIn]
Boas, Walkíria Wingester Vilas [VerfasserIn]
Gomez, Renato Santiago [VerfasserIn]

Links:

Volltext

Themen:

Analgesics, Opioid
Anestesia balanceada
Anestesia intravenosa
Anesthesia recovery
Anesthetics, Combined
Anesthetics, Inhalation
Anesthetics, Intravenous
Balanced anesthesia
CRS35BZ94Q
Comparative Study
Desflurane
Desflurano
Intravenous anesthesia
Journal Article
P10582JYYK
Propofol
Randomized Controlled Trial
Recuperação pós‐anestésica
Remifentanil
YI7VU623SF

Anmerkungen:

Date Completed 28.05.2019

Date Revised 28.05.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.bjan.2017.04.024

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM272320897