The effect of vascular peptide bioregulator on the microcirculation in the brain cortex of old rats

Using a TV device to study brain microcirculation, we found that after a course of vascular peptide bioregulator the density of microvascular network of pia matter of old rats (22-24 months) sensomotor cortex increased about 2,5-2,8 times compared to control old rates; and noradrenaline-induced constriction reactions and acetylcholine-induced dilative reactions of the pial arterioles increased significantly. This perfusion in the tissue of the cerebral cortex is not increased, but the degree of blood oxygen saturation in the microvasculature of this tissue region raised.

Medienart:

Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

Advances in gerontology = Uspekhi gerontologii - 29(2016), 2 vom: 10., Seite 291-296

Sprache:

Russisch

Beteiligte Personen:

Sokolova, I B [VerfasserIn]
Sergeev, I V [VerfasserIn]
Ryzhak, G A [VerfasserIn]
Khavinson, V Kh [VerfasserIn]

Themen:

Angiogenic Proteins
Biological Factors
Brain
Density of microvascular network
Journal Article
Old animals
Protective Agents
Reactivity arterioles
Vascular peptide bioregulator

Anmerkungen:

Date Completed 08.02.2018

Date Revised 08.02.2018

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM271989920