Experience with a rheumatoid arthritis biobank : analysis of biological samples and clinical data of 204 patients

INTRODUCTION: A biobank is a registry, which is suitable for the storage of biological samples (e.g. tissues, DNA, protein), genetical abnormalities and clinical data. Several biobanks have been created worldwide, which contribute to research and the better understanding of disease pathogenesis, genetical polymorphisms. Biobanking also helps to improve the efficacy of therapies.

AIM: Our purpose was to create an internet-based biobank, in which laboratory test results, genetic alterations and related disorders of rheumatoid arthritis (RA) patients can be registered. This biobank would be able to make the research easier and it can help to improve our knowledge about diseases and it can inhibit loss of data.

PATIENTS AND METHOD: We have biological samples from 204 RA patients and we have entered their data in the biobank which can be found on the website http://rheuma.biobank.eu . Statistical analysis was performed by SPSS20 statistical programme.

RESULTS: By the creation of biobank that contains clinical data and biological samples of 204 RA patients, we have a database which can help to improve our knowledge about the disease and help to develop new treatment strategies.

CONCLUSION: Biobanking is suitable to analyze blood samples and clinical data together. Orv. Hetil., 2017, 158(7), 270-277.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:158

Enthalten in:

Orvosi hetilap - 158(2017), 7 vom: 15. Feb., Seite 270-277

Sprache:

Ungarisch

Weiterer Titel:

Rheumatoid arthritises biobankkal szerzett tapasztalataink: 204 beteg biológiai mintáinak és klinikai adatainak összevetése

Beteiligte Personen:

Pál, Ildikó [VerfasserIn]
Pusztai, Anita [VerfasserIn]
Csomor, Péter [VerfasserIn]
Szekanecz, Zoltán [VerfasserIn]

Links:

Volltext

Themen:

Biobank
Genetic polymorphism
Genetikai polimorfizmus
HLA genes
HLA-gének
Journal Article
Rheumatoid arthritis

Anmerkungen:

Date Completed 03.08.2017

Date Revised 03.08.2017

published: Print

Citation Status MEDLINE

doi:

10.1556/650.2017.30650

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM271483806