Metastatic prostate carcinoma to the orbit as the first presentation of disease
Prostate carcinoma is a common tumor of the older adult male. It is associated with bony metastases, particularly to the axial skeleton. We present two case histories; in both cases, the patients had no prior history of prostate carcinoma. Both cases were diagnosed with CT imaging, elevated PSA, and biopsy. Additionally, they were treated with surgical resection and hormone modulation therapy. While bony metastases are frequently associated with advanced disease, they can also be a cause of presenting symptoms. The CT imaging in these two cases showed the classic hyperostotic findings of prostate cancer. Prostate cancer may cause osteoblastic lesions in contrast to other metastatic bone lesions, which cause destructive osteolytic lesions. During excisional surgery, the tumor was inspected and many stalactite-like lesions were present on the gross sample. We present these and compare them to the CT imaging.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2017 |
|---|---|
| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
|---|---|
| Enthalten in: |
Orbit (Amsterdam, Netherlands) - 36(2017), 4 vom: 01. Aug., Seite 234-236 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
AufderHeide, Adam C [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Case Reports |
|---|
| Anmerkungen: |
Date Completed 19.03.2018 Date Revised 22.11.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1080/01676830.2017.1310257 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM271452307 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM271452307 | ||
| 003 | DE-627 | ||
| 005 | 20231224232731.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/01676830.2017.1310257 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0904.xml |
| 035 | |a (DE-627)NLM271452307 | ||
| 035 | |a (NLM)28459392 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a AufderHeide, Adam C |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Metastatic prostate carcinoma to the orbit as the first presentation of disease |
| 264 | 1 | |c 2017 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 19.03.2018 | ||
| 500 | |a Date Revised 22.11.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Prostate carcinoma is a common tumor of the older adult male. It is associated with bony metastases, particularly to the axial skeleton. We present two case histories; in both cases, the patients had no prior history of prostate carcinoma. Both cases were diagnosed with CT imaging, elevated PSA, and biopsy. Additionally, they were treated with surgical resection and hormone modulation therapy. While bony metastases are frequently associated with advanced disease, they can also be a cause of presenting symptoms. The CT imaging in these two cases showed the classic hyperostotic findings of prostate cancer. Prostate cancer may cause osteoblastic lesions in contrast to other metastatic bone lesions, which cause destructive osteolytic lesions. During excisional surgery, the tumor was inspected and many stalactite-like lesions were present on the gross sample. We present these and compare them to the CT imaging | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Metastatic prostate carcinoma | |
| 650 | 4 | |a orbit | |
| 650 | 4 | |a orbital mass | |
| 650 | 4 | |a prostate | |
| 650 | 7 | |a KLK3 protein, human |2 NLM | |
| 650 | 7 | |a EC 3.4.21.- |2 NLM | |
| 650 | 7 | |a Kallikreins |2 NLM | |
| 650 | 7 | |a EC 3.4.21.- |2 NLM | |
| 650 | 7 | |a Prostate-Specific Antigen |2 NLM | |
| 650 | 7 | |a EC 3.4.21.77 |2 NLM | |
| 700 | 1 | |a Bernard, Benjamin J |e verfasserin |4 aut | |
| 700 | 1 | |a Mollman, Reid A |e verfasserin |4 aut | |
| 700 | 1 | |a Hromas, Alan R |e verfasserin |4 aut | |
| 700 | 1 | |a Camarata, Paul J |e verfasserin |4 aut | |
| 700 | 1 | |a Hylton, Phillip D |e verfasserin |4 aut | |
| 700 | 1 | |a Ebersole, Koji C |e verfasserin |4 aut | |
| 700 | 1 | |a Sokol, Jason A |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Orbit (Amsterdam, Netherlands) |d 1994 |g 36(2017), 4 vom: 01. Aug., Seite 234-236 |w (DE-627)NLM08276090X |x 1744-5108 |7 nnns |
| 773 | 1 | 8 | |g volume:36 |g year:2017 |g number:4 |g day:01 |g month:08 |g pages:234-236 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/01676830.2017.1310257 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 36 |j 2017 |e 4 |b 01 |c 08 |h 234-236 | ||