Maternal immunisation : collaborating with mother nature

Copyright © 2017 Elsevier Ltd. All rights reserved..

Maternal immunisation has the potential to substantially reduce morbidity and mortality from infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation during pregnancy has led to consideration of additional maternal immunisation strategies to prevent group B streptococcus and respiratory syncytial virus infections, among others. However, many gaps in knowledge regarding the immunobiology of maternal immunisation prevent the optimal design and application of this successful public health intervention. Therefore, we did an innovative landscape analysis to identify research priorities. Key topics were delineated through review of the published literature, consultation with vaccine developers and regulatory agencies, and a collaborative workshop that gathered experts across several maternal immunisation initiatives-group B streptococcus, respiratory syncytial virus, pertussis, and influenza. Finally, a global online survey prioritised the identified knowledge gaps on the basis of expert opinion about their importance and relevance. Here we present the results of this worldwide landscape analysis and discuss the identified research gaps.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:17

Enthalten in:

The Lancet. Infectious diseases - 17(2017), 7 vom: 01. Juli, Seite e197-e208

Sprache:

Englisch

Beteiligte Personen:

Marchant, Arnaud [VerfasserIn]
Sadarangani, Manish [VerfasserIn]
Garand, Mathieu [VerfasserIn]
Dauby, Nicolas [VerfasserIn]
Verhasselt, Valerie [VerfasserIn]
Pereira, Lenore [VerfasserIn]
Bjornson, Gordean [VerfasserIn]
Jones, Christine E [VerfasserIn]
Halperin, Scott A [VerfasserIn]
Edwards, Kathryn M [VerfasserIn]
Heath, Paul [VerfasserIn]
Openshaw, Peter J [VerfasserIn]
Scheifele, David W [VerfasserIn]
Kollmann, Tobias R [VerfasserIn]

Links:

Volltext

Themen:

Influenza Vaccines
Journal Article
Respiratory Syncytial Virus Vaccines
Review
Streptococcal Vaccines

Anmerkungen:

Date Completed 10.07.2017

Date Revised 14.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/S1473-3099(17)30229-3

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM271201347