The alpha-gal syndrome : an allergic reaction to mammalian meat secondary to a tick bite
Here we present the case of a 68-year-old patient with alpha-gal syndrome. This is a delayed-onset allergic reaction, characteristically occurring 2-6 hours after ingestion of mammalian meat products. The reaction occurs because the patient has developed IgE antibodies to a mammalian oligosaccharide epitope, galactose-α-1,3-galactose (alpha-gal); tick bites induce this IgE antibody response. Presentation varies from chronic urticaria to life-threatening anaphylaxis. The alpha-gal syndrome is usually self-limiting as long as there are no new tick bites. Clinicians should be aware of this syndrome, which is often not recognized as such.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:161 |
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| Enthalten in: |
Nederlands tijdschrift voor geneeskunde - 161(2017) vom: 15., Seite D1062 |
| Sprache: |
Niederländisch |
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| Weiterer Titel: |
Het alfa-galsyndroom, allergische reacties op vlees |
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| Beteiligte Personen: |
Berends, A M A [VerfasserIn] |
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| Themen: |
37341-29-0 |
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| Anmerkungen: |
Date Completed 27.07.2018 Date Revised 26.09.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM269854622 |
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| 245 | 1 | 4 | |a The alpha-gal syndrome |b an allergic reaction to mammalian meat secondary to a tick bite |
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| 500 | |a Date Revised 26.09.2019 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Here we present the case of a 68-year-old patient with alpha-gal syndrome. This is a delayed-onset allergic reaction, characteristically occurring 2-6 hours after ingestion of mammalian meat products. The reaction occurs because the patient has developed IgE antibodies to a mammalian oligosaccharide epitope, galactose-α-1,3-galactose (alpha-gal); tick bites induce this IgE antibody response. Presentation varies from chronic urticaria to life-threatening anaphylaxis. The alpha-gal syndrome is usually self-limiting as long as there are no new tick bites. Clinicians should be aware of this syndrome, which is often not recognized as such | ||
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