First successful perinatal management of pregnancy after ABO-incompatible liver transplantation

Many papers have reported on pregnancy and delivery after liver transplantation, but there have been no reports on pregnancy after ABO-incompatible liver transplantation. This paper reports the first successful pregnancy and delivery of a newborn after ABO-incompatible liver transplantation for fulminant hepatic failure. The patient was a 39-year-old female. She had an ABO-incompatible liver transplantation, donated from her husband, due to subacute fulminant hepatitis of unknown etiology. She was taking tacrolimus, methylprednisolone, and mizoribine orally for the maintenance of immunosuppression at the time of discharge. She was discharged uneventfully on postoperative day 38 without any rejection episodes. At 1 year and 6 mo after transplantation, she indicated a wish to become pregnant. Therefore, treatment with mycophenolate mofetil was interrupted at that time. After two miscarriages, she finally became pregnant and delivered transvaginally 3 years after the transplantation. All of the pregnancies were conceived naturally. The newborn was female with a birth weight of 3146 g; the Apgar scores were 9 and 10. Delivery was performed smoothly, and the newborn exhibited no malformations. The mother and the newborn were discharged uneventfully. We suggest that pregnancy is possible for recipients after ABO-incompatible liver transplantation.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:23

Enthalten in:

World journal of gastroenterology - 23(2017), 3 vom: 21. Jan., Seite 547-550

Sprache:

Englisch

Beteiligte Personen:

Higashi, Hisanobu [VerfasserIn]
Obara, Hideaki [VerfasserIn]
Miyakoshi, Kei [VerfasserIn]
Shinoda, Masahiro [VerfasserIn]
Kitago, Minoru [VerfasserIn]
Shimojima, Naoki [VerfasserIn]
Abe, Yuta [VerfasserIn]
Hibi, Taizo [VerfasserIn]
Yagi, Hiroshi [VerfasserIn]
Matsubara, Kentaro [VerfasserIn]
Yamada, Yohei [VerfasserIn]
Itano, Osamu [VerfasserIn]
Hoshino, Ken [VerfasserIn]
Kuroda, Tatsuo [VerfasserIn]
Kitagawa, Yuko [VerfasserIn]

Links:

Volltext

Themen:

4F4X42SYQ6
4JR41A10VP
ABO Blood-Group System
ABO-incompatible
Case Reports
Delivery
Fulminant hepatic failure
Immunosuppressive Agents
Journal Article
Liver transplantation
Living donor
Methylprednisolone
Mizoribine
Pregnancy
Ribonucleosides
Rituximab
Tacrolimus
WM0HAQ4WNM
X4W7ZR7023

Anmerkungen:

Date Completed 17.07.2017

Date Revised 04.12.2021

published: Print

Citation Status MEDLINE

doi:

10.3748/wjg.v23.i3.547

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM269047093