ARResT/Interrogate : an interactive immunoprofiler for IG/TR NGS data
Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task.
Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.
Availability and Implementation: ARResT/Interrogate is implemented primarily in R, and is freely available at http://bat.infspire.org/arrest/interrogate/.
Contact: nikos.darzentasgmail.com.
Supplementary Information: Supplementary data are available at Bioinformatics online.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
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| Enthalten in: |
Bioinformatics (Oxford, England) - 33(2017), 3 vom: 01. Feb., Seite 435-437 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bystry, Vojtech [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 10.08.2018 Date Revised 02.12.2018 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/bioinformatics/btw634 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM268744246 |
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| 520 | |a Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task | ||
| 520 | |a Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations | ||
| 520 | |a Availability and Implementation: ARResT/Interrogate is implemented primarily in R, and is freely available at http://bat.infspire.org/arrest/interrogate/ | ||
| 520 | |a Contact: nikos.darzentasgmail.com | ||
| 520 | |a Supplementary Information: Supplementary data are available at Bioinformatics online | ||
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| 700 | 1 | |a Krejci, Adam |e verfasserin |4 aut | |
| 700 | 1 | |a Demko, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Hanakova, Barbora |e verfasserin |4 aut | |
| 700 | 1 | |a Grioni, Andrea |e verfasserin |4 aut | |
| 700 | 1 | |a Knecht, Henrik |e verfasserin |4 aut | |
| 700 | 1 | |a Schlitt, Max |e verfasserin |4 aut | |
| 700 | 1 | |a Dreger, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Sellner, Leopold |e verfasserin |4 aut | |
| 700 | 1 | |a Herrmann, Dietrich |e verfasserin |4 aut | |
| 700 | 1 | |a Pingeon, Marine |e verfasserin |4 aut | |
| 700 | 1 | |a Boudjoghra, Myriam |e verfasserin |4 aut | |
| 700 | 1 | |a Rijntjes, Jos |e verfasserin |4 aut | |
| 700 | 1 | |a Pott, Christiane |e verfasserin |4 aut | |
| 700 | 1 | |a Langerak, Anton W |e verfasserin |4 aut | |
| 700 | 1 | |a Groenen, Patricia J T A |e verfasserin |4 aut | |
| 700 | 1 | |a Davi, Frederic |e verfasserin |4 aut | |
| 700 | 1 | |a Brüggemann, Monika |e verfasserin |4 aut | |
| 700 | 1 | |a Darzentas, Nikos |e verfasserin |4 aut | |
| 700 | 0 | |a EuroClonality-NGS |e verfasserin |4 aut | |
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