The Carbapenemase-Producing Klebsiella pneumoniae Population Is Distinct and More Clonal than the Carbapenem-Susceptible Population

Copyright © 2017 American Society for Microbiology..

We studied in parallel the population structure of 90 carbapenemase-producing and 88 carbapenemase-susceptible Klebsiella pneumoniae isolates collected in 20 Spanish hospitals, in the context of the EuSCAPE project. Fourteen and 50 multilocus sequence types (MLSTs) were detected among the carbapenemase-producing and carbapenem-susceptible isolates, respectively. ST11 and ST15 clones were more frequent in the carbapenemase-producing group than in the carbapenemase-susceptible group (P < 0.0001). Among the members of the carbapenem-suceptible group, the cefotaxime-resistant population showed population parameters that differed between the populations of the wild-type strains and the carbapenemase producers.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:61

Enthalten in:

Antimicrobial agents and chemotherapy - 61(2017), 4 vom: 30. Apr.

Sprache:

Englisch

Beteiligte Personen:

Esteban-Cantos, Andrés [VerfasserIn]
Aracil, Belén [VerfasserIn]
Bautista, Verónica [VerfasserIn]
Ortega, Adriana [VerfasserIn]
Lara, Noelia [VerfasserIn]
Saez, David [VerfasserIn]
Fernández-Romero, Sara [VerfasserIn]
Pérez-Vázquez, María [VerfasserIn]
Navarro, Ferran [VerfasserIn]
Grundmann, Hajo [VerfasserIn]
Campos, José [VerfasserIn]
Oteo, Jesús [VerfasserIn]
EuSCAPE-Spain Network [VerfasserIn]
Alarcón, Teresa [Sonstige Person]
Barba, Isabel [Sonstige Person]
Cercenado, Emilia [Sonstige Person]
de Miguel, M. Antonia [Sonstige Person]
Fontanals, Dionisia [Sonstige Person]
Fleites, Ana M. [Sonstige Person]
Sánchez-Romero, Isabel [Sonstige Person]
Solís, Sonia [Sonstige Person]
Gimeno, Adelina [Sonstige Person]
Hernández, Juan Manuel [Sonstige Person]
Martínez-López, Jesús [Sonstige Person]
Navarro, Ferran [Sonstige Person]
Alós, Juan Ignacio [Sonstige Person]
Arias, Marta [Sonstige Person]
Yagüe, Genoveva [Sonstige Person]
Sainz de Baranda, Caridad [Sonstige Person]
Cordón, Luz Albina [Sonstige Person]
Leiva, José [Sonstige Person]
Pérez-Moreno, Mar Olga [Sonstige Person]

Links:

Volltext

Themen:

Anti-Bacterial Agents
Bacterial Proteins
Beta-Lactamases
Carbapenem resistance
Carbapenemase
Carbapenemases
Carbapenems
Cefotaxime
EC 3.5.2.6
Journal Article
Klebsiella pneumoniae
MLST
N2GI8B1GK7
Population structure

Anmerkungen:

Date Completed 25.09.2017

Date Revised 09.12.2020

published: Electronic-Print

Citation Status MEDLINE

doi:

10.1128/AAC.02520-16

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM268474982