Spectrum of Xanthogranulomatous Processes in the Abdomen and Pelvis : A Pictorial Review of Infectious, Inflammatory, and Proliferative Responses

OBJECTIVE: Xanthogranulomatous (XG) processes are rare inflammatory conditions with the characteristic pathologic feature of lipid-laden macrophages or histiocyte cells. Imaging findings are nonspecific and can simulate aggressive neoplastic processes. XG processes can be caused by infection, inflammation, histolytic process, or an inherited lysosomal disorder. XG infectious processes are mainly seen in cholecystitis and pyelonephritis, but several other organs can also be involved. Histiocytic processes can be divided into Langerhans and non-Langerhans cell histiocytosis. The non-Langerhans cell histiocytosis entities include Erdheim-Chester disease, Rosai-Dorfman disease, juvenile xanthogranuloma, and hemophagocytic lymphohistiocytosis. The inherited lysosomal disorders resulting in XG processes include Nieman-Pick, Gaucher, and other lysosomal storage disorders.

CONCLUSION: Radiologists need to be able to recognize features of xanthogranulomatous processes to help facilitate patient management.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:208

Enthalten in:

AJR. American journal of roentgenology - 208(2017), 3 vom: 22. März, Seite 475-484

Sprache:

Englisch

Beteiligte Personen:

Bourm, Kelsey S [VerfasserIn]
Menias, Christine O [VerfasserIn]
Ali, Kamran [VerfasserIn]
Alhalabi, Kinan [VerfasserIn]
Elsayes, Khaled M [VerfasserIn]

Links:

Volltext

Themen:

Cholecystitis
Erdheim-Chester disease
Hemophagocytic lymphohistiocytosis
Infection
Inflammation
Journal Article
Juvenile xanthogranuloma
Pyelonephritis
Review
Rosai-Dorfman disease
Xanthogranulomatous process

Anmerkungen:

Date Completed 03.04.2017

Date Revised 21.03.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2214/AJR.16.17075

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM268072124