MicroRNA annotation of plant genomes - Do it right or not at all

© 2017 The Authors BioEssays Published by WILEY Periodicals, Inc..

MicroRNAs are non-coding regulators of gene expression and key factors in development, disease, and targets for bioengineering. Consequently, microRNAs have become essential elements of already burgeoning draft plant genome descriptions where their annotation is often particularly poor, contributing unduly to the corruption of public databases. Using the Citrus sinensis as an example, we highlight and review common failings of miRNAome annotations. Understanding and exploiting the role of miRNAs in plant biology will be stymied unless the research community acts decisively to improve the accuracy of miRNAome annotations. We encourage genome annotation teams to do it right or not at all.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:39

Enthalten in:

BioEssays : news and reviews in molecular, cellular and developmental biology - 39(2017), 2 vom: 15. Feb.

Sprache:

Englisch

Beteiligte Personen:

Taylor, Richard S [VerfasserIn]
Tarver, James E [VerfasserIn]
Foroozani, Alireza [VerfasserIn]
Donoghue, Philip C J [VerfasserIn]

Links:

Volltext

Themen:

Annotation
Citrus
Evolution
Genome
Journal Article
MiRBase
MicroRNA
MicroRNAs
Mis-annotation
Plant
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 22.11.2017

Date Revised 09.03.2018

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/bies.201600113

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM267698623