Efficacy and safety of ultrasound-guided radiofrequency ablation of hyperplastic parathyroid gland for secondary hyperparathyroidism associated with chronic kidney disease
© 2016 Wiley Periodicals, Inc..
BACKGROUND: The purpose of this study was to determine if ultrasound-guided radiofrequency ablation (RFA) of hyperplastic parathyroid glands could be used to treat secondary hyperparathyroidism (HPT) in patients with chronic kidney disease.
METHODS: RFA of the hyperplastic parathyroid glands was performed in 34 patients with secondary HPT. Intact parathyroid hormone (iPTH), calcium, and phosphorus were measured. The outcome was based on the ablation extent (ie, 4, 3, and 1-2 glands).
RESULTS: The iPTH, calcium, and phosphorus levels decreased in all groups after RFA. One year after ablation, these parameters remained significantly lower in the 4-gland ablation group compared with the 3-gland and 1 to 2-gland groups. The same tendency was observed for the symptom score. The iPTH levels of <272 pg/mL on the day after ablation was the best predictor for maintaining parathyroid hormone (PTH) levels in a reasonable range 1 year after ablation.
CONCLUSIONS: RFA of hyperplastic parathyroid glands for treating secondary HPT is feasible in selected patients. © 2016 Wiley Periodicals, Inc. Head Neck 39: 564-571, 2017.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:39 |
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| Enthalten in: |
Head & neck - 39(2017), 3 vom: 13. März, Seite 564-571 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Peng, Chengzhong [VerfasserIn] |
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| Links: |
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| Themen: |
Chronic kidney disease |
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| Anmerkungen: |
Date Completed 05.03.2018 Date Revised 22.07.2018 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/hed.24657 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM267550561 |
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| 500 | |a Date Revised 22.07.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2016 Wiley Periodicals, Inc. | ||
| 520 | |a BACKGROUND: The purpose of this study was to determine if ultrasound-guided radiofrequency ablation (RFA) of hyperplastic parathyroid glands could be used to treat secondary hyperparathyroidism (HPT) in patients with chronic kidney disease | ||
| 520 | |a METHODS: RFA of the hyperplastic parathyroid glands was performed in 34 patients with secondary HPT. Intact parathyroid hormone (iPTH), calcium, and phosphorus were measured. The outcome was based on the ablation extent (ie, 4, 3, and 1-2 glands) | ||
| 520 | |a RESULTS: The iPTH, calcium, and phosphorus levels decreased in all groups after RFA. One year after ablation, these parameters remained significantly lower in the 4-gland ablation group compared with the 3-gland and 1 to 2-gland groups. The same tendency was observed for the symptom score. The iPTH levels of <272 pg/mL on the day after ablation was the best predictor for maintaining parathyroid hormone (PTH) levels in a reasonable range 1 year after ablation | ||
| 520 | |a CONCLUSIONS: RFA of hyperplastic parathyroid glands for treating secondary HPT is feasible in selected patients. © 2016 Wiley Periodicals, Inc. Head Neck 39: 564-571, 2017 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a chronic kidney disease | |
| 650 | 4 | |a hyperplastic parathyroid gland | |
| 650 | 4 | |a intact parathyroid hormone | |
| 650 | 4 | |a radiofrequency ablation | |
| 650 | 4 | |a secondary hyperparathyroidism | |
| 700 | 1 | |a Zhang, Zhengxian |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Jibin |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Hongyu |e verfasserin |4 aut | |
| 700 | 1 | |a Tu, Xiao |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Rihong |e verfasserin |4 aut | |
| 700 | 1 | |a Ni, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Weng, Ning |e verfasserin |4 aut | |
| 700 | 1 | |a Pang, Haisu |e verfasserin |4 aut | |
| 700 | 1 | |a Xue, Zhengmei |e verfasserin |4 aut | |
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