Structure elucidation and analysis of biosynthesis genes of the O-antigen of Escherichia coli O131 containing N-acetylneuraminic acid

Copyright © 2016 Elsevier Ltd. All rights reserved..

The O-polysaccharide (O-antigen) of Escherichia coli O131 was studied by sugar analysis along with 1D and 2D 1H and 13C NMR spectroscopy. The following structure of the linear tetrasaccharide repeating unit of the polysaccharide was established: →8)-α-Neup5Ac-(2 → 6)-β-D-Galp-(1 → 6)-β-D-Galp-(1 → 3)-β-D-GalpNAc-(1→ The gene functions were tentatively assigned by comparison with sequences in the available databases and found to be in agreement with the E. coli O131-antigen structure.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:436

Enthalten in:

Carbohydrate research - 436(2016) vom: 21. Dez., Seite 41-44

Sprache:

Englisch

Beteiligte Personen:

Perepelov, Andrei V [VerfasserIn]
Guo, Xi [VerfasserIn]
Senchenkova, Sof'ya N [VerfasserIn]
Shashkov, Alexander S [VerfasserIn]
Liu, Bin [VerfasserIn]
Knirel, Yuriy A [VerfasserIn]

Links:

Volltext

Themen:

Bacterial polysaccharide structure
Escherichia coli
GZP2782OP0
Journal Article
Lipopolysaccharide
N-Acetylneuraminic Acid
N-acetylneuraminic acid
O Antigens
O-antigen gene cluster
O-polysaccharide structure
Oligosaccharides

Anmerkungen:

Date Completed 07.02.2017

Date Revised 07.02.2017

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.carres.2016.11.003

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM266342906