A retrospective case-control study of immunoglobulin G4-related disease combined with malignancy

IgG4-related disease (IgG4-RD) has been proved to be associated with malignancy.The incidence and risk factors of malignancy development in IgG4-RD were not clear. Nine IgG4-RD patients with malignancies and 27 IgG4-RD control cases were analyzed for risk factors and clinical features. The incidence of malignancy in IgG4-RD was 3.3%, higher than age-controlled general population. Smoking history was significantly more common in patients with malignancies than in the control group (9/9 vs 16/27, P<0.05). A total of 6/9 malignancies occurred within the first year after the diagnosis of IgG4-RD. Colorectal, biliary and thyroid cancers were the leading types. Smoking history is a risk factor for IgG4-RD associated malignancy. Careful vigilance to monitor malignancy needs to be paid during follow-up.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:55

Enthalten in:

Zhonghua nei ke za zhi - 55(2016), 11 vom: 01. Nov., Seite 869-871

Sprache:

Chinesisch

Beteiligte Personen:

Feng, Y L [VerfasserIn]
Wu, D [VerfasserIn]
Zhang, S Y [VerfasserIn]
Wu, X [VerfasserIn]
Shu, H J [VerfasserIn]
Yang, A M [VerfasserIn]
Qian, J M [VerfasserIn]

Links:

Volltext

Themen:

Immunoglobulin G
Journal Article

Anmerkungen:

Date Completed 30.06.2017

Date Revised 02.12.2018

published: Print

Citation Status MEDLINE

doi:

10.3760/cma.j.issn.0578-1426.2016.11.011

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM265821495