Second pancreatectomy for recurrent pancreatic ductal adenocarcinoma in the remnant pancreas : A pooled analysis
Copyright © 2016 IAP and EPC. Published by Elsevier B.V. All rights reserved..
OBJECTIVES: The aim of this study was to examine the outcomes of second pancreatectomy for the treatment of recurrent pancreatic ductal adenocarcinoma (PDAC) in the remnant pancreas.
METHOD: Search of the PubMed database was undertaken to identify relevant English language studies. Pooled individually data were examined for clinical outcomes after second pancreatectomy for recurrent PDAC.
RESULTS: A total of 19 articles involving 55 patients were eligible for inclusion. The median disease-free interval after initial resection was 33 (range 7-143) months. Of the 55 patients reported, 52 (94.5%) patients underwent completion total pancreatectomy in the second operation for recurrences, including 15 patients who developed recurrences more than 5 years after the initial operation. There was no perioperative death. The 1-, 3- and 5-year overall survival rate after the second pancreatectomy was 82.2%, 49.2% and 40.6% respectively.
CONCLUSION: Second pancreatectomy for recurrent PDAC can be performed safely with long-term survival in selected patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2016 |
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| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al. - 16(2016), 6 vom: 15. Nov., Seite 1124-1128 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhou, Yanming [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 04.04.2017 Date Revised 01.12.2017 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.pan.2016.09.015 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM265116015 |
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| 245 | 1 | 0 | |a Second pancreatectomy for recurrent pancreatic ductal adenocarcinoma in the remnant pancreas |b A pooled analysis |
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| 500 | |a Date Completed 04.04.2017 | ||
| 500 | |a Date Revised 01.12.2017 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2016 IAP and EPC. Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a OBJECTIVES: The aim of this study was to examine the outcomes of second pancreatectomy for the treatment of recurrent pancreatic ductal adenocarcinoma (PDAC) in the remnant pancreas | ||
| 520 | |a METHOD: Search of the PubMed database was undertaken to identify relevant English language studies. Pooled individually data were examined for clinical outcomes after second pancreatectomy for recurrent PDAC | ||
| 520 | |a RESULTS: A total of 19 articles involving 55 patients were eligible for inclusion. The median disease-free interval after initial resection was 33 (range 7-143) months. Of the 55 patients reported, 52 (94.5%) patients underwent completion total pancreatectomy in the second operation for recurrences, including 15 patients who developed recurrences more than 5 years after the initial operation. There was no perioperative death. The 1-, 3- and 5-year overall survival rate after the second pancreatectomy was 82.2%, 49.2% and 40.6% respectively | ||
| 520 | |a CONCLUSION: Second pancreatectomy for recurrent PDAC can be performed safely with long-term survival in selected patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Pancreatectomy | |
| 650 | 4 | |a Pancreatic ductal adenocarcinoma | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Recurrence | |
| 700 | 1 | |a Song, Ailing |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Lupeng |e verfasserin |4 aut | |
| 700 | 1 | |a Si, Xiaoying |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yumin |e verfasserin |4 aut | |
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