Molecularly imprinted polymer membranes and thin films for the separation and sensing of biomacromolecules

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim..

This review describes recent advances associated with the development of surface imprinting methods for the synthesis of polymeric membranes and thin films, which possess the capability to selectively and specifically recognize biomacromolecules, such as proteins and single- and double-stranded DNA, employing "epitope" or "whole molecule" approaches. Synthetic procedures to create different molecularly imprinted polymer membranes or thin films are discussed, including grafting/in situ polymerization, drop-, dip-, or spin-coating procedures, electropolymerization as well as micro-contact or stamp lithography imprinting methods. Highly sensitive techniques for surface characterization and analyte detection are described, encompassing luminescence and fluorescence spectroscopy, X-ray photoelectron spectroscopy, FTIR spectroscopy, surface-enhanced Raman spectroscopy, atomic force microscopy, quartz crystal microbalance analysis, cyclic voltammetry, and surface plasmon resonance. These developments are providing new avenues to produce bioelectronic sensors and new ways to explore through advanced separation science procedures complex phenomena associated with the origins of biorecognition in nature.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:40

Enthalten in:

Journal of separation science - 40(2017), 1 vom: 13. Jan., Seite 314-335

Sprache:

Englisch

Beteiligte Personen:

Boysen, Reinhard I [VerfasserIn]
Schwarz, Lachlan J [VerfasserIn]
Nicolau, Dan V [VerfasserIn]
Hearn, Milton T W [VerfasserIn]

Links:

Volltext

Themen:

Biomacromolecules
Journal Article
Macromolecular Substances
Membranes
Membranes, Artificial
Molecularly imprinted polymers
Polymers
Research Support, Non-U.S. Gov't
Review
Surface imprinting
Thin films

Anmerkungen:

Date Completed 21.12.2017

Date Revised 02.12.2018

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/jssc.201600849

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM264259351