Palladium-Catalyzed Regioselective C8-H Amination of 1-Naphthylamine Derivatives with Aliphatic Amines

A simple and facile protocol for palladium-catalyzed picolinamide-directed C8-H amination of 1-naphthylamine derivatives with simple secondary aliphatic amines was developed, thereby providing a new route to 1,8-naphthalenediamine derivatives. It is noteworthy that the picolinamide moiety as a bidentate directing group may play a key role in this regioselective transformation.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Organic letters - 18(2016), 18 vom: 16. Sept., Seite 4594-7

Sprache:

Englisch

Beteiligte Personen:

Li, Zexian [VerfasserIn]
Sun, Suyan [VerfasserIn]
Qiao, Huijie [VerfasserIn]
Yang, Fan [VerfasserIn]
Zhu, Yu [VerfasserIn]
Kang, Jianxun [VerfasserIn]
Wu, Yusheng [VerfasserIn]
Wu, Yangjie [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 08.06.2018

Date Revised 08.06.2018

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1021/acs.orglett.6b02243

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM263962997